NADH:cytochrome b5 reductase and cytochrome b5 act as sole electron donors to human cytochrome P450 1A1-catalyzed oxidation and DNA adduct formation by benzo[a]pyrene

2016 ◽  
Vol 258 ◽  
pp. S96
Author(s):  
M. Stiborova ◽  
I. Radek ◽  
M. Moserova ◽  
E. Frei ◽  
K. Kopka ◽  
...  
Keyword(s):  
Cytochrome P450 ◽  
Cytochrome B5 ◽  
Adduct Formation ◽  
Dna Adduct ◽  
Electron Donors ◽  
Cytochrome P450 1A1 ◽  
Human Cytochrome ◽  
Catalyzed Oxidation

scholarly journals Cytochrome b5 and epoxide hydrolase contribute to benzo[a]pyrene-DNA adduct formation catalyzed by cytochrome P450 1A1 under low NADPH:P450 oxidoreductase conditions

Toxicology ◽  
2014 ◽  
Vol 318 ◽  
pp. 1-12 ◽  
Author(s):  
Marie Stiborová ◽  
Michaela Moserová ◽  
Věra Černá ◽  
Radek Indra ◽  
Martin Dračínský ◽  
...  
Keyword(s):  
Cytochrome P450 ◽  
Epoxide Hydrolase ◽  
Cytochrome B5 ◽  
Adduct Formation ◽  
Dna Adduct ◽  
Cytochrome P450 1A1

DNA adduct formation by the environmental contaminant 3-nitrobenzanthrone in V79 cells expressing human cytochrome P450 enzymes

2003 ◽  
Vol 200 (1) ◽  
pp. 9-18 ◽  
Author(s):  
Christian A Bieler ◽  
Volker M Arlt ◽  
Manfred Wiessler ◽  
Heinz H Schmeiser
Keyword(s):  
Cytochrome P450 ◽  
Adduct Formation ◽  
Dna Adduct ◽  
Environmental Contaminant ◽  
Cytochrome P450 Enzymes ◽  
V79 Cells ◽  
Human Cytochrome

Stable Expression of Human Cytochrome P450 1B1 in V79 Chinese Hamster Cells and Metabolically Catalyzed DNA Adduct Formation of Dibenzo[a,l]pyrene

1998 ◽  
Vol 11 (6) ◽  
pp. 686-695 ◽  
Author(s):  
Andreas Luch ◽  
Stephanie L. Coffing ◽  
Yong M. Tang ◽  
Anneliese Schneider ◽  
Volker Soballa ◽  
...  
Keyword(s):  
Cytochrome P450 ◽  
Chinese Hamster ◽  
Adduct Formation ◽  
Dna Adduct ◽  
Stable Expression ◽  
Chinese Hamster Cells ◽  
Cytochrome P450 1B1 ◽  
Human Cytochrome

A quantitative comparison of dibenzo[a,l]pyrene-DNA adduct formation by recombinant human cytochrome P450 microsomes

1999 ◽  
Vol 26 (2) ◽  
pp. 74-82 ◽  
Author(s):  
Leon C. King ◽  
Linda Adams ◽  
Joycelyn Allison ◽  
Michael J. Kohan ◽  
Garret Nelson ◽  
...  
Keyword(s):  
Cytochrome P450 ◽  
Adduct Formation ◽  
Quantitative Comparison ◽  
Dna Adduct ◽  
Human Cytochrome

scholarly journals The relationship between DNA adduct formation by benzo[a]pyrene and expression of its activation enzyme cytochrome P450 1A1 in rat

2013 ◽  
Vol 36 (3) ◽  
pp. 989-996 ◽  
Author(s):  
Petr Hodek ◽  
Jitka Koblihová ◽  
René Kizek ◽  
Eva Frei ◽  
Volker M. Arlt ◽  
...  
Keyword(s):  
Cytochrome P450 ◽  
Adduct Formation ◽  
Dna Adduct ◽  
Cytochrome P450 1A1 ◽  
The Relationship

scholarly journals NADPH- and NADH-dependent metabolism of and DNA adduct formation by benzo[a]pyrene catalyzed with rat hepatic microsomes and cytochrome P450 1A1

2016 ◽  
Vol 147 (5) ◽  
pp. 847-855 ◽  
Author(s):  
Marie Stiborová ◽  
Radek Indra ◽  
Michaela Moserová ◽  
Miroslav Šulc ◽  
Petr Hodek ◽  
...  
Keyword(s):  
Cytochrome P450 ◽  
Adduct Formation ◽  
Dna Adduct ◽  
Cytochrome P450 1A1 ◽  
Hepatic Microsomes
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