Impact of lymph node ratio and clinico-pathologic parameters on stage IIIC endometrial cancer prognosis: A validation study

2012 ◽  
Vol 125 ◽  
pp. S146-S147
Author(s):  
S. Polterauer ◽  
S. Khalil ◽  
O. Zivanovic ◽  
N. Abu-Rustum ◽  
A. Reinthaller ◽  
...  
2012 ◽  
Vol 119 (6) ◽  
pp. 1210-1218 ◽  
Author(s):  
Stephan Polterauer ◽  
Susan Khalil ◽  
Oliver Zivanovic ◽  
Nadeem R. Abu-Rustum ◽  
Gerda Hofstetter ◽  
...  

2021 ◽  
Author(s):  
Cem Onal ◽  
Sezin Yuce Sari ◽  
Guler Yavas ◽  
Ozan Cem Guler ◽  
Ecem Yigit ◽  
...  

Aim: To evaluate the prognostic value of the lymph node ratio (LNR) and other clinicopathological factors in patients with stage IIIC endometrial cancer. Methods: Factors affecting overall survival (OS) and progression-free survival (PFS) were assessed in 397 patients with stage IIIC endometrial cancer treated with postoperative radiotherapy. Patients undergoing the removal of at least ten lymph nodes were included in the study. Results: The 5-year OS and PFS rates were 58% and 52%, respectively, with a median follow-up time of 35.7 months. The LNR cutoff value was 9.6%. In the multivariate analysis, advanced age (≥60 years), grade III tumor, presence of cervical stromal invasion, higher LNR and lack of adjuvant chemotherapy were independent predictors for worse OS and PFS. Conclusion: The LNR is an independent predictor for OS and PFS in patients with stage IIIC endometrial cancer treated with postoperative radiotherapy.


Breast Cancer ◽  
2013 ◽  
Vol 21 (1) ◽  
pp. 1-9 ◽  
Author(s):  
Dechun Liu ◽  
Yanbin Chen ◽  
Miao Deng ◽  
Gangqiang Xie ◽  
Jianguang Wang ◽  
...  

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