scholarly journals 518. Long-Term Lentiviral Vector-Mediated Transgene Expression in Neural Progenitor Cells Following Implantation into the Injured Rat Spinal Cord

2004 ◽  
Vol 9 ◽  
pp. S196
Keyword(s):  
Spinal Cord ◽  
Progenitor Cells ◽  
Transgene Expression ◽  
Neural Progenitor Cells ◽  
Lentiviral Vector ◽  
Neural Progenitor ◽  
Rat Spinal Cord

scholarly journals Long-term transgene expression in mouse neural progenitor cells modified with ϕC31 integrase

2008 ◽  
Vol 173 (2) ◽  
pp. 299-305 ◽  
Author(s):  
Annahita Keravala ◽  
Brandi K. Ormerod ◽  
Theo D. Palmer ◽  
Michele P. Calos
Keyword(s):  
Progenitor Cells ◽  
Transgene Expression ◽  
Neural Progenitor Cells ◽  
Neural Progenitor

scholarly journals Chondroitinase ABC Treatment and the Phenotype of Neural Progenitor Cells Isolated From Injured Rat Spinal Cord

2011 ◽  
pp. 705-708 ◽  
Author(s):  
L. SLOVINSKÁ ◽  
I. NOVOTNÁ ◽  
D. ČÍŽKOVÁ
Keyword(s):  
Spinal Cord ◽  
Progenitor Cells ◽  
Neural Progenitor Cells ◽  
Neural Progenitor ◽  
Cns Injury ◽  
Rat Spinal Cord ◽  
Chondroitinase Abc ◽  
Differentiation Potential ◽  
Cord Injury ◽  
The Impact

The aim of the present study was to investigate whether enzyme chondroitinase ABC (ChABC) treatment influences the phenotype of neural progenitor cells (NPCs) derived from injured rat spinal cord. Adult as well as fetal spinal cords contain a pool of endogenous neural progenitors cells, which play a key role in the neuroregenerative processes following spinal cord injury (SCI) and hold particular promise for therapeutic approaches in CNS injury or neurodegenerative disorders. In our study we used in vitro model to demonstrate the differentiation potential of NPCs isolated from adult rat spinal cord after SCI, treated with ChABC. The intrathecal delivery of ChABC (10 U/ml) was performed at day 1 and 2 after SCI. The present findings indicate that the impact of SCI resulted in a decrease of all NPCs phenotypes and the ChABC treatment, on the contrary, caused an opposite effect.

Impact of chemokines on the properties of spinal cord-derived neural progenitor cells in a rat spinal cord lesion model

2014 ◽  
Vol 93 (4) ◽  
pp. 562-571 ◽  
Author(s):  
Friederike Knerlich-Lukoschus ◽  
Sebastian Krossa ◽  
Jörg Krause ◽  
H. Maximilian Mehdorn ◽  
Axel Scheidig ◽  
...  
Keyword(s):  
Spinal Cord ◽  
Progenitor Cells ◽  
Neural Progenitor Cells ◽  
Neural Progenitor ◽  
Spinal Cord Lesion ◽  
Rat Spinal Cord ◽  
Cord Lesion

scholarly journals Human Oligodendrogenic Neural Progenitor Cells Delivered with Chondroitinase ABC Facilitate Functional Repair of Chronic Spinal Cord Injury

2018 ◽  
Vol 11 (6) ◽  
pp. 1433-1448 ◽  
Author(s):  
Satoshi Nori ◽  
Mohamad Khazaei ◽  
Christopher S. Ahuja ◽  
Kazuya Yokota ◽  
Jan-Eric Ahlfors ◽  
...  
Keyword(s):  
Spinal Cord ◽  
Spinal Cord Injury ◽  
Progenitor Cells ◽  
Neural Progenitor Cells ◽  
Neural Progenitor ◽  
Chronic Spinal Cord Injury ◽  
Chondroitinase Abc ◽  
Cord Injury
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