Antianginal efficacy of carvedilol, a beta-blocking drug with vasodilating activity

1986 ◽  
Vol 58 (10) ◽  
pp. 916-921 ◽  
Author(s):  
Erwin A. Rodrigues ◽  
Avijit Lahiri ◽  
Liam O. Hughes ◽  
Ravinder S. Kohli ◽  
John R. Whittington ◽  
...  
1985 ◽  
Vol 56 (1) ◽  
pp. 35-40 ◽  
Author(s):  
Juan Carlos Kaski ◽  
Luis Rodriguez-Plaza ◽  
John Brown ◽  
Attilio Maseri

1984 ◽  
Vol 107 (5) ◽  
pp. 888-895 ◽  
Author(s):  
Paul Touboul ◽  
Georges Atallah ◽  
Gilbert Kirkorian ◽  
Michel Lamaud ◽  
Pierre Moleur

1981 ◽  
Vol 74 (4) ◽  
pp. 278-282 ◽  
Author(s):  
A M Joekes ◽  
F D Thompson ◽  
P F B O'Regan

The powerful peripheral vasodilator minoxidil, in a dose of 5-40 mg daily, controlled the previously refractory blood pressure in 45 out of 47 patients for periods up to fifty-seven months. The majority of the previous polypharmacy was withdrawn, leaving most of the patients taking a beta-blocking drug, minoxidil and a diuretic. Severe sodium retention leading to congestive cardiac failure necessitated the withdrawal of the drug in 3 patients. In one patient the drug was discontinued because of postural hypotension, and it was withdrawn in 2 female patients because of hirsutism. Five patients were removed from the trial as they were started on chronic maintenance haemodialysis or received a renal transplant. Significant glucose intolerance developed in one patient, requiring the addition of an oral hypoglycaemic agent. The 4 deaths that occurred were not directly related to treatment. Following the oral administration of 5 mg minoxidil, an obvious reduction in both the systolic and diastolic pressure was seen in two hours.


1979 ◽  
Vol 98 (5) ◽  
pp. 604-612 ◽  
Author(s):  
J.L. Rod ◽  
D. Admon ◽  
A. Kimchi ◽  
M.S. Gotsman ◽  
B.S. Lewis

1969 ◽  
Vol 55 (3) ◽  
pp. 182-183
Author(s):  
Alfred Soffer
Keyword(s):  

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