Serial measurements of antineutrophil cytoplasmic autoantibodies in patients with systemic vasculitis

1999 ◽  
Vol 106 (5) ◽  
pp. 527-533 ◽  
Author(s):  
Xavier Kyndt ◽  
Dominique Reumaux ◽  
Franck Bridoux ◽  
Bruno Tribout ◽  
Pierre Bataille ◽  
...  
Keyword(s):  
Systemic Vasculitis ◽  
Antineutrophil Cytoplasmic Autoantibodies ◽  
Serial Measurements

Antineutrophil cytoplasmic autoantibodies, autoantigens, and systemic vasculitis

Apmis ◽  
1995 ◽  
Vol 103 (1-6) ◽  
pp. 81-97 ◽  
Author(s):  
WOLFGANG L. Gross ◽  
ELENA Csernok ◽  
UDO Helmchen
Keyword(s):  
Systemic Vasculitis ◽  
Antineutrophil Cytoplasmic Autoantibodies

scholarly journals A Case of Granulomatosis with Polyangiitis Causing Hydroureter and Hydronephrosis

2014 ◽  
Vol 2014 ◽  
pp. 1-3
Author(s):  
Farzin Farpour ◽  
Adriana Abrudescu
Keyword(s):  
Iliac Artery ◽  
Lower Respiratory Tract ◽  
Granulomatosis With Polyangiitis ◽  
Common Iliac Artery ◽  
Systemic Vasculitis ◽  
Serine Proteinase ◽  
Proteinase 3 ◽  
Necrotizing Glomerulonephritis ◽  
The Right ◽  
Antineutrophil Cytoplasmic Autoantibodies

Granulomatosis with Polyangiitis (GPA, formerly known as Wegener) is a systemic vasculitis characterized by granulomatous involving upper and lower respiratory tract and can also cause necrotizing glomerulonephritis (Umemoto et al. 2012 and Takala et al. 2011). GPA is associated with antineutrophil cytoplasmic autoantibodies (ANCA) against serine proteinase 3 (PR3) (Takala et al. 2011, Dufour et al. 2012, and Berthoux et al. 2011). This disease usually starts with involvement of the upper and lower respiratory tracts and also can involve kidney, eyes, skin, central and peripheral nervous systems, and gastrointestinal tract (Umemoto et al. 2012, Takala et al. 2011, and Berthoux et al. 2011). We describe a case of GPA that presented with abdominal pain. Computed tomography (CT) scan with contrast showed right sided moderate hydronephrosis and hydroureter, to the level of the right common iliac artery. There was also mural segmental thickening in common iliac artery which was thought to be the cause of the ureteral obstruction and hydronephrosis. Our case shows that mural segmental thickening in common iliac artery happened due to GPA and caused hydronephrosis. In addition, most of the cases with hydronephrosis due to GPA went through urology intervention such as stent placement but in our case hydronephrosis resolved with medical management.

scholarly journals Systemic vasculitis with antineutrophil cytoplasmic autoantibodies (ANCA) in three dental technicians

1997 ◽  
Vol 12 (3) ◽  
pp. 578-581 ◽  
Author(s):  
G. Grateau ◽  
C. Bachmeyer ◽  
O. Kourilsky ◽  
V. Gomez ◽  
G. Choukroun ◽  
...  
Keyword(s):  
Systemic Vasculitis ◽  
Antineutrophil Cytoplasmic Autoantibodies

EFFECTS OF SYNTHETIC LH/FSH-RELEASING HORMONE (LRH) ON PLASMA LH AND FSH IN AMENORRHOEIC WOMEN

1974 ◽  
Vol 75 (4) ◽  
pp. 647-652 ◽  
Author(s):  
G. Rannevik ◽  
J. Thorell
Keyword(s):  
Urinary Excretion ◽  
Initial Response ◽  
Releasing Hormone ◽  
The Mean ◽  
The Difference ◽  
Serial Measurements

ABSTRACT Eight amenorrhoeic women were given 100 μg synthetic LRH (Hoechst) iv and im, respectively, at an interval of 2 weeks. Four of the women received the iv injection first and four the im injection. The urinary excretion of oestrogens and pregnanediol was low and unaltered throughout the test weeks. The effects of LRH were compared by serial measurements of the plasma LH and FSH during 8 h. The initial response of LH for up to 25 min and that of FSH for up to 60 min were equal whether LRH was given iv or im. The difference appeared later. Four hours after the injection the mean increase of LH to iv injection was 0.5 ng/ml (N. S.), while that to im injection was 1.9 ng/ml (P < 0.01). The corresponding values for FSH were 1.3 (P < 0.05) and 3.2 (P < 0.001). The effect of LRH administration im was thus found to be larger and more prolonged.

EFFECTS OF INCREASING DOSES OF PYROGLUTAMYL-HISTIDYL-PROLINE AMIDE ON SERUM THYROTROPHIN LEVELS IN NORMAL SUBJECTS

1972 ◽  
Vol 70 (1) ◽  
pp. 196-208 ◽  
Author(s):  
Bengt Karlberg ◽  
Sven Almqvist
Keyword(s):  
Normal Saline ◽  
Standard Dose ◽  
Normal Subjects ◽  
Response Curves ◽  
Clinical Observations ◽  
Trh Stimulation ◽  
Stimulation Tests ◽  
Serial Measurements ◽  
Serum Tsh ◽  
Stimulation Of

ABSTRACT The effects of the administration of normal saline in four normal subjects and the single iv injections of synthetic pyroglutamyl-histidyl-proline amide (TRH) in doses of 6.25, 12.5, 25, 50, 100, 200 and 400 μg in 12 healthy subjects were evaluated by clinical observations and serial measurements from −10 to + 360 minutes of serum TSH, PBI, STH, cholesterol, glucose and insulin. Normal saline and TRH 6.25 μg iv did not change the serum TSH level. The minimum iv dose of TRH increasing serum TSH within 10 minutes was 12.5 μg. Nine of 12 subjects gave maximal increases of serum TSH after TRH 100 μg and all after 200 and 400 μg. The time for the peak response varied with the dose from 15 to 60 minutes. The dose-response curves, average and individual, were complex and not linear. This was interpreted as a varying degree of stimulation of both pituitary synthesis and release of TSH by TRH. PBI changes were measured at 2 h and 6 h. Minimum dose for a significant increase of PBI was 12.5 μg and 6.25 μg of TRH for the respective times. No change in basal STH-levels occurred in 53 of 65 TRH-stimulation tests. Nine of the 12 changes in serum STH occurred in four subjects with varying basal STH-levels. No changes were found in serum cholesterol, glucose or insulin. Our results show that 50 μg of TRH can be used as a standard dose for the single iv stimulation of pituitary release of TSH. TRH stimulated both TSH and STH release in 18% of our tests.

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