ABSTRACTCold neutron prompt gamma-ray activation analysis has proven useful for nondestructive measurement of trace hydrogen. The sample is irradiated in a beam of neutrons; the presence of hydrogen is confirmed by the emission of a 2223 keV gamma-ray. Detection limits for hydrogen are 3 mg/kg in quartz and 8 mg/kg in titanium. We have used the technique to measure hydrogen in titanium alloys, germanium, quartz, fullerenes and their derivatives, and other materials.