scholarly journals Abundant expression of myosin heavy-chain IIB RNA in a subset of human masseter muscle fibres

2001 ◽  
Vol 46 (11) ◽  
pp. 1039-1050 ◽  
Author(s):  
Michael J Horton ◽  
Carla A Brandon ◽  
Terence J Morris ◽  
Thomas W Braun ◽  
Kenneth M Yaw ◽  
...  
1992 ◽  
Vol 282 (1) ◽  
pp. 237-242 ◽  
Author(s):  
A Jakubiec-Puka ◽  
C Catani ◽  
U Carraro

The myosin heavy-chain (MHC) isoform pattern was studied by biochemical methods in the slow-twitch (soleus) and fast-twitch (gastrocnemius) muscles of adult rats during atrophy after tenotomy and recovery after tendon regeneration. The tenotomized slow muscle atrophied more than the tenotomized fast muscle. During the 12 days after tenotomy the total MHC content decreased by about 85% in the slow muscle, and only by about 35% in the fast muscle. In the slow muscle the ratio of MHC-1 to MHC-2A(2S) remained almost unchanged, showing that similar diminution of both isoforms occurs. In the fast muscle the MHC-2A/MHC-2B ratio decreased, showing the loss of MHC-2A mainly. After tendon regeneration, the slow muscle recovered earlier than the fast muscle. Full recovery of the muscles was not observed until up to 4 months later. The embryonic MHC, which seems to be expressed in denervated adult muscle fibres, was not detected by immunoblotting in the tenotomized muscles during either atrophy or recovery after tendon regeneration. The influence of tenotomy and denervation on expression of the MHC isoforms is compared. The results show that: (a) MHC-1 and MHC-2A(2S) are very sensitive to tenotomy, whereas MHC-2B is much less sensitive; (b) expression of the embryonic MHC in adult muscle seems to be inhibited by the intact neuromuscular junction.


1989 ◽  
Vol 10 (3) ◽  
pp. 197-205 ◽  
Author(s):  
Stefano Schiaffino ◽  
Luisa Gorza ◽  
Saverio Sartore ◽  
Leopoldo Saggin ◽  
Simonetta Ausoni ◽  
...  

2001 ◽  
Vol 80 (9) ◽  
pp. 1845-1848 ◽  
Author(s):  
T.J. Morris ◽  
C.A. Branden ◽  
M.J. Horton ◽  
D.S. Carlson ◽  
J.J. Sciote

2013 ◽  
Vol 122 (4) ◽  
pp. 278-288 ◽  
Author(s):  
Daisuke Umeki ◽  
Yoshiki Ohnuki ◽  
Yasumasa Mototani ◽  
Kouichi Shiozawa ◽  
Takayuki Fujita ◽  
...  

FEBS Letters ◽  
1996 ◽  
Vol 386 (1) ◽  
pp. 87-90 ◽  
Author(s):  
Mehrdad Monemi ◽  
Per-Olof Eriksson ◽  
Ihari Dubail ◽  
Gillian S. Butler-Browne ◽  
Lars-Erik Thornell

1991 ◽  
Vol 12 (3) ◽  
pp. 281-291 ◽  
Author(s):  
Julie Ivory Rushbrook ◽  
Cipora Weiss ◽  
Tsai-Tse Yao

2014 ◽  
Vol 592 (24) ◽  
pp. 5461-5475 ◽  
Author(s):  
Yoshiki Ohnuki ◽  
Daisuke Umeki ◽  
Yasumasa Mototani ◽  
Huiling Jin ◽  
Wenqian Cai ◽  
...  

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