scholarly journals Altered kinetics of contraction in skeletal muscle fibers containing a mutant myosin regulatory light chain with reduced divalent cation binding

1996 ◽  
Vol 71 (1) ◽  
pp. 341-350 ◽  
Author(s):  
G.M. Diffee ◽  
J.R. Patel ◽  
F.C. Reinach ◽  
M.L. Greaser ◽  
R.L. Moss
Keyword(s):  
Skeletal Muscle ◽  
Divalent Cation ◽  
Light Chain ◽  
Muscle Fibers ◽  
Regulatory Light Chain ◽  
Cation Binding ◽  
Myosin Regulatory Light Chain ◽  
Skeletal Muscle Fibers ◽  
Kinetics Of

scholarly journals Orientation of the N-Terminal Lobe of the Myosin Regulatory Light Chain in Skeletal Muscle Fibers

2012 ◽  
Vol 102 (6) ◽  
pp. 1418-1426 ◽  
Author(s):  
Daniela Romano ◽  
Birgit D. Brandmeier ◽  
Yin-Biao Sun ◽  
David R. Trentham ◽  
Malcolm Irving
Keyword(s):  
Skeletal Muscle ◽  
Light Chain ◽  
Muscle Fibers ◽  
Regulatory Light Chain ◽  
Myosin Regulatory Light Chain ◽  
Skeletal Muscle Fibers

scholarly journals Fluorescence Polarization Transients from Rhodamine Isomers on the Myosin Regulatory Light Chain in Skeletal Muscle Fibers

1998 ◽  
Vol 74 (6) ◽  
pp. 3093-3110 ◽  
Author(s):  
Seth C. Hopkins ◽  
Cibele Sabido-David ◽  
John E.T. Corrie ◽  
Malcolm Irving ◽  
Yale E. Goldman
Keyword(s):  
Skeletal Muscle ◽  
Light Chain ◽  
Fluorescence Polarization ◽  
Muscle Fibers ◽  
Regulatory Light Chain ◽  
Myosin Regulatory Light Chain ◽  
Skeletal Muscle Fibers

scholarly journals Bifunctional Rhodamine Probes of Myosin Regulatory Light Chain Orientation in Relaxed Skeletal Muscle Fibers

2004 ◽  
Vol 86 (4) ◽  
pp. 2329-2341 ◽  
Author(s):  
Andrew S. Brack ◽  
Birgit D. Brandmeier ◽  
Roisean E. Ferguson ◽  
Susan Criddle ◽  
Robert E. Dale ◽  
...  
Keyword(s):  
Skeletal Muscle ◽  
Light Chain ◽  
Muscle Fibers ◽  
Regulatory Light Chain ◽  
Myosin Regulatory Light Chain ◽  
Chain Orientation ◽  
Skeletal Muscle Fibers

Determinants of relaxation rate in skinned frog skeletal muscle fibers

1998 ◽  
Vol 274 (6) ◽  
pp. C1608-C1615 ◽  
Author(s):  
Philip A. Wahr ◽  
J. David Johnson ◽  
Jack. A. Rall
Keyword(s):  
Skeletal Muscle ◽  
Muscle Fibers ◽  
Slow Phase ◽  
Frog Skeletal Muscle ◽  
Force Of Contraction ◽  
Thin Filaments ◽  
Fast Phase ◽  
Skeletal Muscle Fibers ◽  
Kinetics Of ◽  
Overall Kinetics

The influences of sarcomere uniformity and Ca2+ concentration on the kinetics of relaxation were examined in skinned frog skeletal muscle fibers induced to relax by rapid sequestration of Ca2+ by the photolysis of the Ca2+ chelator, diazo-2, at 10°C. Compared with an intact fiber, diazo-2-induced relaxation exhibited a faster and shorter initial slow phase and a fast phase with a longer tail. Stabilization of the sarcomeres by repeated releases and restretches during force development increased the duration of the slow phase and slowed its kinetics. When force of contraction was decreased by lowering the Ca2+concentration, the overall kinetics of relaxation was accelerated, with the slow phase being the most sensitive to Ca2+ concentration. Twitchlike contractions were induced by photorelease of Ca2+ from a caged Ca2+ (DM-Nitrophen), with subsequent Ca2+ sequestration by intact sarcoplasmic reticulum or Ca2+ rebinding to caged Ca2+. These twitchlike responses exhibited relaxation kinetics that were about twofold slower than those observed in intact fibers. Results suggest that the slow phase of relaxation is influenced by the degree of sarcomere homogeneity and rate of Ca2+ dissociation from thin filaments. The fast phase of relaxation is in part determined by the level of Ca2+ activation.

scholarly journals Kinetics of contractile activation in voltage clamped frog skeletal muscle fibers

1997 ◽  
Vol 73 (4) ◽  
pp. 1999-2011 ◽  
Author(s):  
P. Szentesi ◽  
Z. Papp ◽  
G. Szücs ◽  
L. Kovács ◽  
L. Csernoch
Keyword(s):  
Skeletal Muscle ◽  
Muscle Fibers ◽  
Frog Skeletal Muscle ◽  
Skeletal Muscle Fibers ◽  
Contractile Activation ◽  
Kinetics Of
Sign in / Sign up

Export Citation Format

Share Document