Comparison of hepatic iron content in African Americans and Caucasians with hepatitis C.

2001 ◽  
Vol 120 (5) ◽  
pp. A571-A571
Author(s):  
J SCHWARTZ ◽  
V FISHMAN ◽  
R THOMAS ◽  
J GAUGHN ◽  
K KOWDLEY ◽  
...  
Keyword(s):  
Hepatitis C ◽  
African Americans ◽  
Iron Content ◽  
Hepatic Iron

Comparison of hepatic iron content in African Americans and Caucasians with hepatitis C.

2001 ◽  
Vol 120 (5) ◽  
pp. A571
Author(s):  
Jonathan M. Schwartz ◽  
Victor Fishman ◽  
Rebecca M. Thomas ◽  
John Gaughn ◽  
Kris V. Kowdley ◽  
...  
Keyword(s):  
Hepatitis C ◽  
African Americans ◽  
Iron Content ◽  
Hepatic Iron

Intrahepatic Iron Variation May Greatly Affect the Hepatic Iron Index

1996 ◽  
Vol 3 (4) ◽  
pp. 263-266
Author(s):  
Pedram Argani ◽  
Emma E. Furth
Keyword(s):  
Hepatitis C ◽  
Iron Content ◽  
False Positive ◽  
Gold Standard ◽  
Hepatic Iron ◽  
Small Areas ◽  
Histologic Grading ◽  
Paraffin Block ◽  
Positive Results

The quantitative hepatic iron index is considered the gold standard for the diagnosis of primary hemochromatosis. While intrahepatic variability in the amount of stainable iron in histologic sections of liver is well known, the quantitative variability has not been addressed. Eight native livers removed at transplantation for cirrhosis associated with hepatitis C were studied. Iron-stained sections from multiple different areas of each liver were examined, and small areas were graded for iron content on a scale of 0 to 4. The fragments of liver corresponding to these were then cut out of the corresponding section of the paraffin block and sent for iron quantitation. We found that marked quantitative heterogeneity in iron content (>260%) can exist in a given liver, leading, in two cases, to false positive results for the diagnosis of hemochromatosis. In addition, it was found that quantitative iron content did indeed linearly correlate with histologic grading. Thus, intrahepatic variation in iron content in a given liver is yet another reason to interpret the hepatic iron index with caution.

1001 Relationship between hepatic iron content and histological response in chronic hepatitis C

Hepatology ◽  
2003 ◽  
Vol 38 ◽  
pp. 639-639
Author(s):  
S RULYAK ◽  
S ENG ◽  
K PATEL ◽  
J MCHUTCHISON ◽  
S GORDON ◽  
...  
Keyword(s):  
Chronic Hepatitis ◽  
Hepatitis C ◽  
Chronic Hepatitis C ◽  
Iron Content ◽  
Hepatic Iron ◽  
Histological Response

African Americans Are Less Likely to Have Clearance of Hepatitis C Virus Infection

2012 ◽  
Vol 46 (8) ◽  
pp. e62-e65 ◽  
Author(s):  
Heshaam M. Mir ◽  
Maria Stepanova ◽  
Mariam Afendy ◽  
Marcelo Kugelmas ◽  
Zobair M. Younossi
Keyword(s):  
Hepatitis C Virus ◽  
Hepatitis C ◽  
African Americans ◽  
Virus Infection ◽  
Hepatitis C Virus Infection

scholarly journals Branched‐chain amino acids reduce hepatic iron accumulation and oxidative stress in hepatitis C virus polyprotein‐expressing mice

2014 ◽  
Vol 35 (4) ◽  
pp. 1303-1314 ◽  
Author(s):  
Masaaki Korenaga ◽  
Sohji Nishina ◽  
Keiko Korenaga ◽  
Yasuyuki Tomiyama ◽  
Naoko Yoshioka ◽  
...  
Keyword(s):  
Oxidative Stress ◽  
Amino Acids ◽  
Hepatitis C Virus ◽  
Hepatitis C ◽  
Branched Chain Amino Acids ◽  
Iron Accumulation ◽  
Hepatic Iron ◽  
Branched Chain ◽  
Virus Polyprotein ◽  
And Oxidative Stress

Increase in hepatic iron stores following prolonged therapy with ribavirin in patients with chronic hepatitis C

1994 ◽  
Vol 21 (6) ◽  
pp. 1109-1112 ◽  
Author(s):  
Adrian M. Di Bisceglie ◽  
Bruce R. Bacon ◽  
David E. Kleiner ◽  
Jay H. Hoofnagle
Keyword(s):  
Chronic Hepatitis ◽  
Hepatitis C ◽  
Chronic Hepatitis C ◽  
Hepatic Iron ◽  
Iron Stores ◽  
Prolonged Therapy
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