Reactions at the polymerase active site that contribute to the fidelity of Escherichia coli DNA polymerase I (Klenow fragment).

Journal of Biological Chemistry ◽

10.1016/s0021-9258(18)35792-2 ◽

1992 ◽

Vol 267 (34) ◽

pp. 24485-24500 ◽

Author(s):

C.M. Joyce ◽

X.C. Sun ◽

N.D. Grindley

Keyword(s):

Escherichia Coli ◽

Dna Polymerase ◽

Active Site ◽

Klenow Fragment ◽

Dna Polymerase I ◽

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Fluorescent oligonucleotides and deoxynucleotide triphosphates: preparation and their interaction with the large (Klenow) fragment of Escherichia coli DNA polymerase I

Biochemistry ◽

10.1021/bi00437a014 ◽

1989 ◽

Vol 28 (11) ◽

pp. 4601-4607 ◽

Author(s):

Dwayne J. Allen ◽

Paul L. Darke ◽

Stephen J. Benkovic

Keyword(s):

Escherichia Coli ◽

Dna Polymerase ◽

Klenow Fragment ◽

Dna Polymerase I ◽

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The 3′-5′ exonuclease of DNA polymerase I of Escherichia coli: contribution of each amino acid at the active site to the reaction.

The EMBO Journal ◽

10.1002/j.1460-2075.1991.tb07916.x ◽

1991 ◽

Vol 10 (1) ◽

pp. 17-24 ◽

Author(s):

V. Derbyshire ◽

N. D. Grindley ◽

C. M. Joyce

Keyword(s):

Escherichia Coli ◽

Dna Polymerase ◽

Active Site ◽

Dna Polymerase I ◽

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Restoration of the DNA damage resistance of Deinococcus radiodurans DNA polymerase mutants by Escherichia coli DNA polymerase I and Klenow fragment

Mutation Research/DNA Repair ◽

10.1016/0921-8777(94)90064-7 ◽

1994 ◽

Vol 314 (1) ◽

pp. 87-97 ◽

Author(s):

Pabol D. Gutman ◽

Pinhas Fuchs ◽

Kenneth W. Minton

Keyword(s):

Escherichia Coli ◽

Dna Polymerase ◽

Deinococcus Radiodurans ◽

Klenow Fragment ◽

Dna Polymerase I ◽

Damage Resistance ◽

Polymerase I ◽

Polymerase Mutants

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The excision of AP sites by the 3'-5' exonuclease activity of the Klenow fragment of Escherichia coli DNA polymerase I

FEBS Letters ◽

10.1016/0014-5793(84)80605-5 ◽

1984 ◽

Vol 178 (2) ◽

pp. 223-227 ◽

Author(s):

Véronique Bailly ◽

Walter G. Verly

Keyword(s):

Escherichia Coli ◽

Dna Polymerase ◽

Exonuclease Activity ◽

Klenow Fragment ◽

Dna Polymerase I ◽

Ap Sites ◽

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Active Site Interactions Impact Phosphoryl Transfer during Replication of Damaged and Undamaged DNA by Escherichia coli DNA Polymerase I

Chemical Research in Toxicology ◽

10.1021/acs.chemrestox.7b00257 ◽

2017 ◽

Vol 30 (11) ◽

pp. 2033-2043

Author(s):

A. S. Prakasha Gowda ◽

Thomas E. Spratt

Keyword(s):

Escherichia Coli ◽

Dna Polymerase ◽

Active Site ◽

Phosphoryl Transfer ◽

Dna Polymerase I ◽

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Continuous microspectrophotometric measurement of DNA polymerase activity: application to the Klenow fragment of Escherichia coli DNA polymerase I and human immunodeficiency virus type 1 reverse transcriptase.

Proceedings of the National Academy of Sciences ◽

10.1073/pnas.88.3.1014 ◽

1991 ◽

Vol 88 (3) ◽

pp. 1014-1018 ◽

Author(s):

J. G. Baillon ◽

N. T. Nashed ◽

J. M. Sayer ◽

D. M. Jerina

Keyword(s):

Escherichia Coli ◽

Human Immunodeficiency Virus ◽

Reverse Transcriptase ◽

Dna Polymerase ◽

Polymerase Activity ◽

Klenow Fragment ◽

Dna Polymerase I ◽

Immunodeficiency Virus ◽

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A molecular model of the complete three-dimensional structure of the Klenow fragment of Escherichia coli DNA polymerase I: binding of the dNTP substrate and template-primer

Biochemistry ◽

10.1021/bi00126a006 ◽

1992 ◽

Vol 31 (11) ◽

pp. 2879-2886 ◽

Author(s):

Prem N. S. Yadav ◽

Janardan S. Yadav ◽

Mukund J. Modak

Keyword(s):

Escherichia Coli ◽

Dna Polymerase ◽

Molecular Model ◽

Three Dimensional ◽

Dimensional Structure ◽

Klenow Fragment ◽

Dna Polymerase I ◽

Three Dimensional Structure ◽

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Utilization of 2′-Deoxy-6-thioguanosine 5′-Triphosphate In DNA Synthesis Catalyzed by DNA Polymerase I Klenow Fragment of Escherichia Coli

Nucleosides and Nucleotides ◽

10.1080/07328319208021150 ◽

1992 ◽

Vol 11 (1) ◽

pp. 23-35 ◽

Author(s):

Yi-He Ling ◽

J. Arly Nelson ◽

David Farquhar ◽

Kenneth L. Beattie

Keyword(s):

Escherichia Coli ◽

Dna Synthesis ◽

Dna Polymerase ◽

Klenow Fragment ◽

Dna Polymerase I ◽

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Mechanism of the idling-turnover reaction of the large (Klenow) fragment of Escherichia coli DNA polymerase I.

Proceedings of the National Academy of Sciences ◽

10.1073/pnas.83.2.231 ◽

1986 ◽

Vol 83 (2) ◽

pp. 231-235 ◽

Author(s):

V. Mizrahi ◽

P. A. Benkovic ◽

S. J. Benkovic

Keyword(s):

Escherichia Coli ◽

Dna Polymerase ◽

Klenow Fragment ◽

Dna Polymerase I ◽

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Role of the 5´ → 3´ exonuclease and Klenow fragment of Escherichia coli DNA polymerase I in base mismatch repair

Molecular Genetics and Genomics ◽

10.1007/s00438-007-0239-8 ◽

2007 ◽

Vol 278 (2) ◽

pp. 211-220 ◽

Author(s):

Masaru Imai ◽

Yu-ichiro Tago ◽

Makoto Ihara ◽

Masakado Kawata ◽

Kazuo Yamamoto

Keyword(s):

Escherichia Coli ◽

Mismatch Repair ◽

Dna Polymerase ◽

Klenow Fragment ◽

Dna Polymerase I ◽

Base Mismatch ◽

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