Automated high-resolution gas chromatographic analysis of psychotropic drugs in biological fluids using open-tubular glass capillary columns

1977 ◽  
Vol 131 ◽  
pp. 347-355 ◽  
Author(s):  
E. Bailey ◽  
M. Fenoughty ◽  
L. Richardson
Keyword(s):  
High Resolution ◽  
Psychotropic Drugs ◽  
Chromatographic Analysis ◽  
Biological Fluids ◽  
Capillary Columns ◽  
Glass Capillary ◽  
Gas Chromatographic Analysis ◽  
Glass Capillary Columns ◽  
Drugs In Biological Fluids

High-Resolution Gas-Chromatographic Analysis of the Volatile Constituents of Body Fluids, with Use of Glass Capillary Columns

1974 ◽  
Vol 20 (9) ◽  
pp. 1105-1110 ◽  
Author(s):  
Milos Novotny ◽  
Michael L McConnell ◽  
Milton L Lee ◽  
Raleigh Farlow
Keyword(s):  
Human Urine ◽  
Chromatographic Analysis ◽  
High Efficiency ◽  
Stationary Phases ◽  
Capillary Columns ◽  
Porous Polymer ◽  
Glass Capillary ◽  
Volatile Constituents ◽  
Glass Capillary Columns ◽  
Glass Columns

Abstract Trace volatile constituents of human urine, serum, and cerebrospinal fluid were concentrated on a porous polymer precolumn, and resolved with high-efficiency glass capillary columns. Thin-film glass columns facilitate effective resolution of underivatized compounds within the volatility range up to docosane in relatively short analysis times. Glass capillary columns coated with stationary phases of different polarity were used. Recorded volatile metabolic profiles of human urine are altered after the sample is treated with β-glucuronidase and sulphatase.

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