Highly active, air-stable palladium catalysts for Kumada–Tamao–Corriu cross-coupling reaction of inactivated aryl chlorides with aryl Grignard reagents

2002 ◽  
Vol 653 (1-2) ◽  
pp. 63-68 ◽  
Author(s):  
George Y Li
Keyword(s):  
Palladium Catalysts ◽  
Coupling Reaction ◽  
Cross Coupling ◽  
Grignard Reagents ◽  
Aryl Chlorides ◽  
Highly Active ◽  
Cross Coupling Reaction

Synthesis, Characterization and Catalytic Utilization of a Ferrocene Diamidodiphosphane

2007 ◽  
Vol 72 (4) ◽  
pp. 453-467 ◽  
Author(s):  
Petr Štěpnička ◽  
Jiří Schulz ◽  
Ivana Císařová ◽  
Karla Fejfarová
Keyword(s):  
Phenylboronic Acid ◽  
Coupling Reaction ◽  
Cross Coupling ◽  
Aryl Halides ◽  
Coupling Reactions ◽  
Aryl Chlorides ◽  
Highly Active ◽  
Aryl Bromides ◽  
Cross Coupling Reaction

Amidation of 1'-(diphenylphosphanyl)ferrocene-1-carboxylic acid (Hdpf) with ethane-1,2-diamine afforded N,N'-ethylenebis[1'-(diphenylphosphanyl)ferrocene-1-carboxamide] (1), which was isolated in free and solvated form, 1·2AcOH. Both 1 and Hdpf were further converted to their respective phosphane sulfides, 2·2AcOH and 3 that were structurally characterized. Testing of the amidophosphane ligands in Suzuki-Miyaura cross-coupling reaction between phenylboronic acid and various aryl halides revealed that catalyst formed in situ from 1 and palladium(II) acetate is highly active in coupling reactions of aryl bromides whilst the corresponding aryl chlorides showed no or only poor conversions. The catalyst based on 2·2AcOH gave markedly lower yields of the coupling products.

scholarly journals Palladium-catalyzed oxidative cross-coupling for the synthesis of α-amino ketones

RSC Advances ◽  
2019 ◽  
Vol 9 (55) ◽  
pp. 32081-32084
Author(s):  
Xiao-Hong Wei ◽  
Zhen-Hua Li ◽  
Lian-Biao Zhao ◽  
Ping Zhang ◽  
Han-Cheng Zhou ◽  
...  
Keyword(s):  
Palladium Catalysts ◽  
Coupling Reaction ◽  
Cross Coupling ◽  
Cross Coupling Reaction ◽  
Palladium Catalyzed

A novel oxidative cross-coupling reaction for the synthesis of α-aryl α-amino ketones in the presence of palladium catalysts using T+BF4− as an oxidant has been developed.

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