AN IMPROVED COPPER-CATALYZED CROSS-COUPLING REACTION OF ALKYL TRIFLATES WITH PRIMARY ALKYL GRIGNARD REAGENTS

2008 ◽  
Vol 40 (3) ◽  
pp. 293-301 ◽  
Author(s):  
Shifa Wang ◽  
Aijun Zhang
Keyword(s):  
Coupling Reaction ◽  
Cross Coupling ◽  
Grignard Reagents ◽  
Cross Coupling Reaction

Regioselective Iron‐Catalysed Cross‐Coupling Reaction of Aryl Propargylic Bromides and Aryl Grignard Reagents

2019 ◽  
Vol 362 (1) ◽  
pp. 146-151 ◽  
Author(s):  
Inés Manjón‐Mata ◽  
M. Teresa Quirós ◽  
Elena Buñuel ◽  
Diego J. Cárdenas
Keyword(s):  
Coupling Reaction ◽  
Cross Coupling ◽  
Grignard Reagents ◽  
Cross Coupling Reaction

scholarly journals Cross-Coupling Reaction of Allylic Ethers with Aryl Grignard Reagents Catalyzed by a Nickel Pincer Complex

Molecules ◽  
2019 ◽  
Vol 24 (12) ◽  
pp. 2296 ◽  
Author(s):  
Toru Hashimoto ◽  
Kei Funatsu ◽  
Atsufumi Ohtani ◽  
Erika Asano ◽  
Yoshitaka Yamaguchi
Keyword(s):  
Coupling Reaction ◽  
Cross Coupling ◽  
Grignard Reagents ◽  
High Yield ◽  
Pincer Complex ◽  
Cross Coupling Reaction ◽  
Allylic Aryl Ethers ◽  
Aryl Ethers ◽  
Type Nickel ◽  
Allylic Ethers

A cross-coupling reaction of allylic aryl ethers with arylmagnesium reagents was investigated using β-aminoketonato- and β-diketiminato-based pincer-type nickel(II) complexes as catalysts. An β-aminoketonato nickel(II) complex bearing a diphenylphosphino group as a third donor effectively catalyzed the reaction to afford the target cross-coupled products, allylbenzene derivatives, in high yield. The regioselective reaction of a variety of substituted cinnamyl ethers proceeded to give the corresponding linear products. In contrast, α- and γ-alkyl substituted allylic ethers afforded a mixture of the linear and branched products. These results indicated that the coupling reaction proceeded via a π-allyl nickel intermediate.

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