Iron Metabolism in Trypanosoma congolense Infection in Zebu Cattle: Serum Iron and Serum Iron-binding Capacity

1973 ◽  
Vol 15 (1) ◽  
pp. 24-32 ◽  
Author(s):  
G. Tartour ◽  
O.F. Idris
Author(s):  
Yuanqing Yang ◽  
Rong Wang ◽  
Hongmin Jiang ◽  
Min Hu ◽  
Aiguo Tang ◽  
...  

Background Abnormalities of iron metabolism in pregnancy pose risks for maternal and fetal health. Robust reference intervals for iron metabolism indices have not been established in a pregnant Chinese population. The purpose of this study was to derive reference intervals for indices of iron metabolism during pregnancy in a Chinese population. Methods A total of 360 healthy pregnant women were recruited and divided into three groups of 120 by gestational age: first trimester (1–13 weeks), second trimester (14–27 weeks) and third trimester (≥28 weeks). An additional 120 healthy non-pregnant women were recruited as the non-pregnant control group. Serum ferritin was measured by electrochemiluminescence immunoassay. Serum iron and total iron-binding capacity were measured by a direct bathophenanthroline method. Transferrin saturation value was calculated with formula TS = SI/TIBC. The reference intervals were established using a non-parametric method. Results In first and second trimesters (combined), the reference intervals for serum ferritin, serum iron, total iron-binding capacity and transferrin saturation are 14.7–184.3 mg/L, 14.50–33.45 µmol/L, 36.53–68.81 µmol/L and 19.04–64.76%, respectively. In the third trimester, the reference intervals for serum ferritin, serum iron, total iron-binding capacity and transferrin saturation are 7.2–122.2 mg/L, 5.83–21.52 µmol/L, 49.40–122.76 µmol/L and 8.22–52.75%, respectively. Conclusion The reference intervals for iron metabolism indices for healthy pregnant Chinese women were established in accordance with CLSI C28-A3 guidelines. This will be a valuable tool for clinical practice and research.


2011 ◽  
Vol 412 (23-24) ◽  
pp. 2261-2266 ◽  
Author(s):  
Katsuya Ikuta ◽  
Satoshi Ito ◽  
Hiroki Tanaka ◽  
Katsunori Sasaki ◽  
Yoshihiro Torimoto ◽  
...  

Author(s):  
THOMAS J. GIOVANNIELLO ◽  
THEODORE PETERS ◽  
EDWARD WAGMAN

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