Conformationally restricted amino acids: Diastereoselective substitution at the β-position of L-tryptophan

1992 ◽  
Vol 33 (42) ◽  
pp. 6251-6254 ◽  
Author(s):  
Milan Bruncko ◽  
David Crich
Keyword(s):  
Amino Acids ◽  
Conformationally Restricted ◽  
Restricted Amino Acids

scholarly journals Protein Segments with Conformationally Restricted Amino Acids Can Control Supramolecular Organization at the Nanoscale

2009 ◽  
Vol 49 (7) ◽  
pp. 1623-1629 ◽  
Author(s):  
David Zanuy ◽  
Gema Ballano ◽  
Ana I. Jiménez ◽  
Jordi Casanovas ◽  
Nurit Haspel ◽  
...  
Keyword(s):  
Amino Acids ◽  
Supramolecular Organization ◽  
Conformationally Restricted ◽  
Restricted Amino Acids

A stereolibrary of conformationally restricted amino acids based on pyrrolidinyl/piperidinyloxazole motifs

2015 ◽  
Vol 21 (6) ◽  
pp. 391-395 ◽  
Author(s):  
Oleksiy S. Artamonov ◽  
Taras Bulda ◽  
Tkhe Kyong Fam ◽  
Evgeniy Y. Slobodyanyuk ◽  
Dmitry M. Volochnyuk ◽  
...  
Keyword(s):  
Amino Acids ◽  
Natural Products ◽  
Drug Discovery ◽  
Carboxylic Acids ◽  
Building Blocks ◽  
Conformationally Restricted ◽  
Lead Compounds ◽  
Restricted Amino Acids

AbstractA stereolibrary of conformationally restricted oxazole-containing amino acids, namely all isomers of 5–pyrrolydinyl- and 5-piperidinyloxazole-4-carboxylic acids, were designed and synthesized in three steps by the reaction of the corresponding N-Boc-protected amino acids and ethyl isocyanoacetate. These natural products-inspired amino acids are valuable building blocks for the synthesis of peptidomimetics and potential lead compounds for drug discovery.

Protein biosynthesis with conformationally restricted amino acids

1993 ◽  
Vol 115 (10) ◽  
pp. 4359-4360 ◽  
Author(s):  
David Mendel ◽  
Jonathan Ellman ◽  
Peter G. Schultz
Keyword(s):  
Amino Acids ◽  
Protein Biosynthesis ◽  
Conformationally Restricted ◽  
Restricted Amino Acids

Modeling and Synthesis of Conformationally Restricted Amino Acids

2004 ◽  
Vol 8 (18) ◽  
pp. 1799-1829 ◽  
Author(s):  
R. Galeazzi ◽  
G. Mobbili ◽  
M. Orena
Keyword(s):  
Amino Acids ◽  
Conformationally Restricted ◽  
Restricted Amino Acids

Synthesis and receptor binding of oxytocin analogs containing conformationally restricted amino acids

2001 ◽  
Vol 8 (1) ◽  
pp. 35-40 ◽  
Author(s):  
Krisztina Bakos ◽  
Judit Havass ◽  
Ferenc Fülöp ◽  
Lajos Gera ◽  
John M. Stewart ◽  
...  
Keyword(s):  
Amino Acids ◽  
Receptor Binding ◽  
Conformationally Restricted ◽  
Restricted Amino Acids

Simple access to novel azetidine-containing conformationally restricted amino acids by chemoselective reduction of β-lactams

2004 ◽  
Vol 45 (10) ◽  
pp. 2193-2196 ◽  
Author(s):  
Guillermo Gerona-Navarro ◽  
Ma Angeles Bonache ◽  
Miriam Alı́as ◽  
Ma Jesús Pérez de Vega ◽  
Ma Teresa Garcı́a-López ◽  
...  
Keyword(s):  
Amino Acids ◽  
Conformationally Restricted ◽  
Restricted Amino Acids
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