A convenient synthesis of 1-(S)-[1′-(S)-(t-butyloxycarbonylamino)-2′-phenylethyl]oxirane. A useful building block in the synthesis of HIV protease inhibitors

Tetrahedron Letters ◽

10.1016/s0040-4039(97)00662-x ◽

1997 ◽

Vol 38 (19) ◽

pp. 3483-3486 ◽

Author(s):

Jonas Brånalt ◽

Ingemar Kvarnström ◽

Björn Classon ◽

Bertil Samuelsson ◽

Ulrika Nillroth ◽

...

Keyword(s):

Protease Inhibitors ◽

Building Block ◽

Hiv Protease ◽

Hiv Protease Inhibitors ◽

Convenient Synthesis

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ChemInform Abstract: A Convenient Synthesis of 1-(S)-(1′-(S)-(t-Butyloxycarbonylamino)-2′- phenylethyl)oxirane. A Useful Building Block in the Synthesis of HIV Protease Inhibitors.

10.1002/chin.199733271 ◽

2010 ◽

Vol 28 (33) ◽

pp. no-no

Author(s):

J. BRAANALT ◽

I. KVARNSTROEM ◽

B. CLASSON ◽

B. SAMUELSSON ◽

U. NILLROTH ◽

...

Keyword(s):

Protease Inhibitors ◽

Building Block ◽

Hiv Protease ◽

Hiv Protease Inhibitors ◽

Convenient Synthesis

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Large scale preparation of (2S,3S)-N-Boc-3-amino-1,2-epoxy-4-phenylbutane: A key building block for HIV-protease inhibitors

Tetrahedron Letters ◽

10.1016/0040-4039(95)00533-i ◽

1995 ◽

Vol 36 (19) ◽

pp. 3317-3320 ◽

Author(s):

Pierre L. Beaulieu ◽

Dominik Wernic ◽

Jean-Simon Duceppe ◽

Yvan Guindon

Keyword(s):

Protease Inhibitors ◽

Building Block ◽

Large Scale ◽

Hiv Protease ◽

Hiv Protease Inhibitors ◽

Large Scale Preparation ◽

Scale Preparation

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ChemInform Abstract: A Convenient Synthesis of 1-(S)-(1′-(S)-(tert-Butyloxycarbonylamino)-2′ -phenylethyl)oxirane, a Versatile Intermediate for the Preparation of Hydroxyethylamine Based HIV Protease Inhibitors.

10.1002/chin.199544224 ◽

2010 ◽

Vol 26 (44) ◽

pp. no-no

Author(s):

B. E. GREEN ◽

X. CHEN ◽

D. W. NORBECK ◽

D. J. KEMPF

Keyword(s):

Protease Inhibitors ◽

Hiv Protease ◽

Hiv Protease Inhibitors ◽

Convenient Synthesis

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A Convenient Synthesis of 1-(S)-[1’-(S)-(t-Butyloxycarbonylamino)-2’-phenylethyl]oxirane, a Versatile Intermediate for the Preparation of Hydroxyethylamine Based HIV Protease Inhibitors

Synlett ◽

10.1055/s-1995-5030 ◽

1995 ◽

Vol 1995 (06) ◽

pp. 613-614 ◽

Author(s):

Brian E. Green ◽

Xiaoqi Chen ◽

Daniel W. Norbeck ◽

Dale J. Kempf

Keyword(s):

Protease Inhibitors ◽

Hiv Protease ◽

Hiv Protease Inhibitors ◽

Convenient Synthesis

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ChemInform Abstract: Large Scale Preparation of (2S,3S)-N-Boc-3-Amino-1,2-epoxy-4- phenylbutane: A Key Building Block for HIV-Protease Inhibitors.

10.1002/chin.199535246 ◽

2010 ◽

Vol 26 (35) ◽

pp. no-no

Author(s):

P. L. BEAULIEU ◽

D. WERNIC ◽

J.-S. DUCEPPE ◽

Y. GUINDON

Keyword(s):

Protease Inhibitors ◽

Building Block ◽

Large Scale ◽

Hiv Protease ◽

Hiv Protease Inhibitors ◽

Large Scale Preparation ◽

Scale Preparation

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ChemInform Abstract: An Expeditious Synthesis of (2R,3S)-3-tert-Butoxycarbonylamino-1- isobutylamino-4-phenyl-2-butanol, a Key Building Block of HIV Protease Inhibitors.

10.1002/chin.199717200 ◽

2010 ◽

Vol 28 (17) ◽

pp. no-no

Author(s):

N. SHIBATA ◽

T. KATOH ◽

S. TERASHIMA

Keyword(s):

Protease Inhibitors ◽

Building Block ◽

Hiv Protease ◽

Hiv Protease Inhibitors

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An expeditious synthesis of (2R,3S)-3-tert-butoxycarbonylamino-1-isobutylamino-4-phenyl-2-butanol, a key building block of HIV protease inhibitors

Tetrahedron Letters ◽

10.1016/s0040-4039(96)02406-9 ◽

1997 ◽

Vol 38 (4) ◽

pp. 619-620 ◽

Author(s):

Norio Shibata ◽

Tadashi Katoh ◽

Shiro Terashima

Keyword(s):

Protease Inhibitors ◽

Building Block ◽

Hiv Protease ◽

Hiv Protease Inhibitors

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Determining and Overcoming Resistance to HIV Protease Inhibitors

Current Drug Targets - Infectious Disorders ◽

10.2174/1568005043340984 ◽

2004 ◽

Vol 4 (2) ◽

pp. 137-152 ◽

Author(s):

Jana Prejdova ◽

Milan Soucek ◽

Jan Konvalinka

Keyword(s):

Protease Inhibitors ◽

Hiv Protease ◽

Hiv Protease Inhibitors

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A QSAR Study of HIV Protease Inhibitors Using Theoretical Descriptors

Current Computer - Aided Drug Design ◽

10.2174/1573409911006040269 ◽

2010 ◽

Vol 6 (4) ◽

pp. 269-282 ◽

Author(s):

Subhash C. Basak ◽

Denise Mills ◽

Rajni Garg ◽

Barun Bhhatarai

Keyword(s):

Protease Inhibitors ◽

Hiv Protease ◽

Hiv Protease Inhibitors ◽

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Simultaneous determination of the HIV protease inhibitors indinavir, amprenavir, saquinavir, ritonavir and nelfinavir in human plasma by high-performance liquid chromatography

Journal of Chromatography B Biomedical Sciences and Applications ◽

10.1016/s0378-4347(00)00617-4 ◽

2001 ◽

Vol 755 (1-2) ◽

pp. 85-89 ◽

Author(s):

Harumi Yamada ◽

Hajime Kotaki ◽

Tetsuya Nakamura ◽

Aikichi Iwamoto

Keyword(s):

High Performance Liquid Chromatography ◽

Liquid Chromatography ◽

Simultaneous Determination ◽

Human Plasma ◽

Protease Inhibitors ◽

High Performance ◽

Hiv Protease ◽

Hiv Protease Inhibitors

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