Amniotic Membrane Transplantation for Ocular Surface Reconstruction in Patients with Chemical and Thermal Burns

Ophthalmology ◽  
1997 ◽  
Vol 104 (12) ◽  
pp. 2068-2076 ◽  
Author(s):  
Jun Shimazaki ◽  
Hao-Yung Yang ◽  
Kazuo Tsubota
Keyword(s):  
Surface Reconstruction ◽  
Amniotic Membrane ◽  
Ocular Surface ◽  
Amniotic Membrane Transplantation ◽  
Thermal Burns ◽  
Ocular Surface Reconstruction

Amniotic Membrane Transplantation for Ocular Surface Reconstruction

2001 ◽  
Vol 21 (4) ◽  
pp. 481-489 ◽  
Author(s):  
S.C.G. Tseng
Keyword(s):  
Surface Reconstruction ◽  
Amniotic Membrane ◽  
Ocular Surface ◽  
Transforming Growth Factor ◽  
Ease Of Use ◽  
Myoblast Differentiation ◽  
Amniotic Membrane Transplantation ◽  
Clinical Effects ◽  
Epithelial Stem Cells ◽  
Ocular Surface Reconstruction

The use of amniotic membrane (or amnion) for transplantation as graft in ocular surface reconstruction is reviewed. This technique has become widespread because of the availability of the amnion, convenience and ease of use, and high and reproducible success rates. The mechanisms of action of the transplantation are varied and include the prolongation and clonogenic maintenance of epithelial progenitor cells, promotion of goblet and non-goblet cell differentiation, exclusion of inflammatory cells with anti-protease activities, suppression of Transforming Growth Factor β signaling and myoblast differentiation of normal fibroblasts. The observed clinical effects include facilitation of epithelialization, maintenance of normal phenotypes, and reduction of inflammation, vascularization and scarring. Amniotic membrane transplantation is being increasingly used as graft for various conjunctival and corneal diseases and as a patch in cases of chemical and thermal burns, refractory and recalcitrant keratitis, and most recently as an excellent substrate for expanding epithelial stem cells ex vivo.

Amniotic membrane transplantation for ocular surface reconstruction

1998 ◽  
Vol 95 (2) ◽  
pp. 114-119 ◽  
Author(s):  
Friedrich E. Kruse ◽  
Klaus Rohrschneider ◽  
Hans E. Völcker
Keyword(s):  
Surface Reconstruction ◽  
Amniotic Membrane ◽  
Ocular Surface ◽  
Amniotic Membrane Transplantation ◽  
Ocular Surface Reconstruction

Sutureless amniotic membrane transplantation for ocular surface reconstruction with a chemically defined bioadhesive

Biomaterials ◽  
2008 ◽  
Vol 29 (19) ◽  
pp. 2923-2931 ◽  
Author(s):  
Maho Takaoka ◽  
Takahiro Nakamura ◽  
Hajime Sugai ◽  
Adam J. Bentley ◽  
Naoki Nakajima ◽  
...  
Keyword(s):  
Surface Reconstruction ◽  
Amniotic Membrane ◽  
Ocular Surface ◽  
Amniotic Membrane Transplantation ◽  
Ocular Surface Reconstruction

Amniotic membrane transplantation for ocular surface reconstruction: indications and outcomes

2007 ◽  
Vol 0 (0) ◽  
pp. 070130044246003-??? ◽  
Author(s):  
V Senthil Maharajan ◽  
Vijay Shanmuganathan ◽  
Alison Currie ◽  
Andrew Hopkinson ◽  
April Powell-Richards ◽  
...  
Keyword(s):  
Surface Reconstruction ◽  
Amniotic Membrane ◽  
Ocular Surface ◽  
Amniotic Membrane Transplantation ◽  
Ocular Surface Reconstruction

Amniotic Membrane Transplantation for Ocular Surface Reconstruction

Cornea ◽  
2005 ◽  
Vol 24 (6) ◽  
pp. 643-653 ◽  
Author(s):  
Merle Fernandes ◽  
Mittanamalli S Sridhar ◽  
Virender S Sangwan ◽  
Gullapalli N Rao
Keyword(s):  
Surface Reconstruction ◽  
Amniotic Membrane ◽  
Ocular Surface ◽  
Amniotic Membrane Transplantation ◽  
Ocular Surface Reconstruction
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