Harbor seal (Phoca vitulina) C-reactive protein (C-RP): purification, characterization of specific monoclonal antibodies and development of an immuno-assay to measure serum C-RP concentrations

1997 ◽  
Vol 59 (1-2) ◽  
pp. 151-162 ◽  
Author(s):  
Christina Funke ◽  
Donald P. King ◽  
Rory M. Brotheridge ◽  
Dieter Adelung ◽  
Jeffrey L. Stott
Keyword(s):  
Monoclonal Antibodies ◽  
Protein C ◽  
Harbor Seal ◽  
Phoca Vitulina ◽  
C Reactive Protein ◽  
Reactive Protein ◽  
Immuno Assay

scholarly journals Isolation and characterization of Limulus C-reactive protein genes.

1986 ◽  
Vol 261 (22) ◽  
pp. 10450-10455 ◽  
Author(s):  
N Y Nguyen ◽  
A Suzuki ◽  
S M Cheng ◽  
G Zon ◽  
T Y Liu
Keyword(s):  
C Reactive Protein ◽  
Reactive Protein ◽  
Isolation And Characterization

scholarly journals FXa Inhibition and Coagulation Changes During DVT Prophylaxis by Enoxaparin Over the Course of a 15-Day Follow-Up in Septic Patients

2009 ◽  
Vol 16 (5) ◽  
pp. 584-590 ◽  
Author(s):  
Zuzana Zenáhlíková ◽  
Jan Kvasnička ◽  
Zuzana Kudrnová ◽  
Magda Sudrová ◽  
Radka Brzežková ◽  
...  
Keyword(s):  
Severe Sepsis ◽  
Protein C ◽  
Factor Xa ◽  
Inclusion Criteria ◽  
C Reactive Protein ◽  
Once Daily ◽  
Reactive Protein ◽  
Factor Xa Inhibition ◽  
The Mean

The objective of our study was to examine the changes in coagulation parameters and inflammatory reaction over the course of 15 days in patients with severe sepsis. We tried to identify mechanisms by which sepsis-induced pathophysiological changes may influence the effectiveness of subcutaneously (SC) administered enoxaparin 40 mg once daily. A total of 16 patients (8 men, 8 women; age 35-83 years) meeting the inclusion criteria of severe sepsis were enrolled in this study. The follow-up was performed on days 1, 2, 3, 6, 9, 12, and 15 of hospitalization at the intensive care unit (ICU). Blood coagulation (activated partial thromboplastin time [aPTT], prothrombin time [PT], fibrinogen, antithrombin (AT), protein C [PC], D-dimer, fragment 1.2 [F1.2], factor Xa [FXa] inhibition) and inflammatory reactants (interleukin 6 [IL-6], C-reactive protein [CRP], orosomucoid, α-1-antitrypsin) were tested. The mean FXa inhibition was 0.17 (±0.17) IU/mL. The arbitrarily established range of FXa inhibition for prophylaxis, 0.2 to 0.4 IU/mL, was reached in 22 cases (20%), while in 74 cases (68%), it was below and in 13 cases (12%) above the aforementioned range. Factor Xa inhibition positively correlated with AT (r = .42; P < .001) and PC (r = .45; P < .001) activities. A negative correlation was found between the FXa inhibition and α-1-antitrypsin concentrations (r = —.33; P = .01) but only in the subgroup with α-1-antitrypsin concentrations ≥2.2 g/L. We confirmed that in most patients with sepsis, the prophylaxis with enoxaparin did not lead to the required FXa inhibition. The inhibition of FXa by enoxaparin depends mainly on the AT and PC activities.

Isolation and Characterization of Two Parasitic Protozoa from a Pacific Harbor Seal (Phoca Vitulina Richardsi) With Meningoencephalomyelitis

2001 ◽  
Vol 87 (4) ◽  
pp. 816-822 ◽  
Author(s):  
Melissa A. Miller ◽  
Karen Sverlow ◽  
Paul R. Crosbie ◽  
Bradd C. Barr ◽  
Linda J. Lowenstine ◽  
...  
Keyword(s):  
Harbor Seal ◽  
Phoca Vitulina ◽  
Parasitic Protozoa ◽  
Isolation And Characterization ◽  
Phoca Vitulina Richardsi

scholarly journals Antipneumococcal effects of C-reactive protein and monoclonal antibodies to pneumococcal cell wall and capsular antigens.

1989 ◽  
Vol 57 (5) ◽  
pp. 1457-1464 ◽  
Author(s):  
D E Briles ◽  
C Forman ◽  
J C Horowitz ◽  
J E Volanakis ◽  
W H Benjamin ◽  
...  
Keyword(s):  
Cell Wall ◽  
Monoclonal Antibodies ◽  
C Reactive Protein ◽  
Reactive Protein ◽  
Capsular Antigens

C-reactive protein decreases expression of thrombomodulin and endothelial protein C receptor in human endothelial cells

Surgery ◽  
2005 ◽  
Vol 138 (2) ◽  
pp. 212-222 ◽  
Author(s):  
Bicheng Nan ◽  
Hui Yang ◽  
Shaoyu Yan ◽  
Peter H. Lin ◽  
Alan B. Lumsden ◽  
...  
Keyword(s):  
Endothelial Cells ◽  
Protein C ◽  
Endothelial Protein C Receptor ◽  
Human Endothelial Cells ◽  
C Reactive Protein ◽  
Reactive Protein

Characterization of antigenic and cytotropic properties of C-reactive protein subunits

1993 ◽  
Vol 116 (6) ◽  
pp. 1512-1514
Author(s):  
P. G. Nazarov ◽  
A. V. Polevshchikov ◽  
L. K. Berestovaya ◽  
I. V. Petrov ◽  
V. V. Ponomarenko
Keyword(s):  
C Reactive Protein ◽  
Protein Subunits ◽  
Reactive Protein

Isolation of canine C-reactive protein and characterization of its properties

1992 ◽  
Vol 30 (4) ◽  
pp. 329-339 ◽  
Author(s):  
S. Yamamoto ◽  
K. Tagata ◽  
H. Nagahata ◽  
Y. Ishikawa ◽  
M. Morimatsu ◽  
...  
Keyword(s):  
C Reactive Protein ◽  
Reactive Protein
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