Pulmonary spindle cell carcinoma: Peculiar clinicopathologic manifestations different from ordinary non-small cell carcinoma

Lung Cancer ◽  
2000 ◽  
Vol 29 (1) ◽  
pp. 216-217
Author(s):  
Y Chang ◽  
C Wu ◽  
Y Lee ◽  
J Shih
2020 ◽  
Vol 8 ◽  
pp. 2050313X2098117
Author(s):  
Esra Nsour ◽  
Ali Al Khader ◽  
Bushra Al-Tarawneh

Small cell carcinoma is a malignant neuroendocrine tumor with aggressive clinical behavior. Histologically, the tumor is characterized by the proliferation of small, round, blue cells. Here, we present the case of a 50-year-old man with a 1-month history of enlarging chest wall mass. Microscopic examination of the lesion revealed a highly cellular neoplasm composed of closely packed, atypical spindle cells with scant cytoplasm, inconspicuous nucleoli, and brisk mitotic activity. The hemangiopericytoma-like vascular pattern was prominent. Areas showing a fibrosarcoma-like fascicular pattern were also observed. The tumor was immunohistochemically positive for TTF1, synaptophysin, and chromogranin, confirming small cell carcinoma. Further investigations revealed a lung origin and widespread metastases. The tumor in this case closely mimicked synovial sarcoma or malignant peripheral nerve sheath tumor. Small cell carcinoma demonstrates a hemangiopericytoma-like pattern that can mimic sarcoma histologically. This is a serious pitfall that can significantly affect the speed of diagnosis and management.


1992 ◽  
Vol 16 (11) ◽  
pp. 1108-1115 ◽  
Author(s):  
Yukari T. Tsubota ◽  
Tokunori Kawaguchi ◽  
Takanobu Hoso ◽  
Eisei Nishino ◽  
William D. Travis

Author(s):  
Jong Chul Hong ◽  
Seo Hee Rha ◽  
Hyun-Jik Lee ◽  
Heon Soo Park

2006 ◽  
Vol 55 (5) ◽  
pp. 477
Author(s):  
In Jae Lee ◽  
Kwang Seok Eom ◽  
Seon Young Jeon ◽  
Im Kyung Hwang ◽  
Yul Lee ◽  
...  

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