The importance of radiation in the primary treatment of merkel cell carcinoma (MCC): A rare cancer network study

2004 ◽  
Vol 60 ◽  
pp. S576-S576
Author(s):  
K BEER ◽  
E FRIEDRICH ◽  
J LAGRANGE ◽  
R ZAUCHA ◽  
M KRENGLI ◽  
...  
Keyword(s):  
Cell Carcinoma ◽  
Merkel Cell Carcinoma ◽  
Primary Treatment ◽  
Merkel Cell ◽  
Rare Cancer ◽  
Cancer Network

The Essential Role of Radiotherapy in the Treatment of Merkel Cell Carcinoma: A Study From the Rare Cancer Network

2011 ◽  
Vol 81 (4) ◽  
pp. e583-e591 ◽  
Author(s):  
Pirus Ghadjar ◽  
Johannes H. Kaanders ◽  
Philipp Poortmans ◽  
Renata Zaucha ◽  
Marco Krengli ◽  
...  
Keyword(s):  
Cell Carcinoma ◽  
Merkel Cell Carcinoma ◽  
Essential Role ◽  
Merkel Cell ◽  
Rare Cancer ◽  
Cancer Network

Immunotherapy in advanced Merkel cell carcinoma: Sydney west cancer network experience

2021 ◽  
Author(s):  
Shaheen Hasmat ◽  
Julie R. Howle ◽  
Deme J. Karikios ◽  
Matteo S. Carlino ◽  
Michael J. Veness
Keyword(s):  
Cell Carcinoma ◽  
Merkel Cell Carcinoma ◽  
Merkel Cell ◽  
Cancer Network

Designing a practice-changing trial for a rare cancer population: The Rational MCC trial of first definitive treatment for Merkel cell carcinoma

2016 ◽  
Vol 42 (11) ◽  
pp. S239-S240
Author(s):  
Rachel Blundred ◽  
Christina Yap ◽  
Carie Corner ◽  
Pat Lawton ◽  
Oliver Cassell ◽  
...  
Keyword(s):  
Cell Carcinoma ◽  
Merkel Cell Carcinoma ◽  
Definitive Treatment ◽  
Merkel Cell ◽  
Rare Cancer

scholarly journals Merkel cell carcinoma associated with chronic treatment with hydroxyurea: a case report

2021 ◽  
Vol 7 (2) ◽  
pp. 289
Author(s):  
Saulo Esteves Saraiva ◽  
Virgínia Mareco ◽  
André Florindo ◽  
Diogo Delgado ◽  
Maria Filomena De Pina
Keyword(s):  
Cell Carcinoma ◽  
Merkel Cell Carcinoma ◽  
Poor Prognosis ◽  
Neuroendocrine Tumour ◽  
External Beam Radiotherapy ◽  
Primary Treatment ◽  
Postoperative Treatment ◽  
Merkel Cell ◽  
Primary Treatment Modality ◽  
Scalp Lesion

<p class="abstract">Merkel cell carcinoma is a rare neuroendocrine tumour of the skin, that shows a quickly and aggressive behaviour and carries a poor prognosis. Surgery is the standard primary treatment modality, while radiotherapy plays a role in postoperative treatment. Radiotherapy is also an alternative to unresectable lesions or patients who are unfit to surgery. Here we report a 90-year-old male with polycythemia vera that was chronically treated with hydroxyurea for about 30 years. The patient presented a purple and exophytic frontal scalp lesion, which had recurred after primary wide excision. This recurrence had been considered inoperable and the patient was treated with external beam radiotherapy to the lesion and locoregional lymph nodes, showing a complete clinical response after 12 weeks. However, disease progressed rapidly, and the patient died from distant metastasis 4 months later. This report is the second described case in literature of Merkel cell carcinoma as complication of chronic hydroxyurea and highlights the need for these patients to undergo regular and close dermatological evaluation.</p>

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