179 Long term quality of life study in prostate cancer patients treated with three dimensional conformal radiation therapy: Bowel and bladder quality of life symptoms are similar to that of the normal population

1999 ◽  
Vol 45 (3) ◽  
pp. 240 ◽  
Author(s):  
A.L. Hanlon ◽  
D.W. Bruner ◽  
G.E. Hanks
Keyword(s):  
Quality Of Life ◽  
Prostate Cancer ◽  
Radiation Therapy ◽  
Cancer Patients ◽  
Normal Population ◽  
Three Dimensional ◽  
Conformal Radiation Therapy ◽  
Life Study

A meta-analysis of health-related quality of life after primary treatment for prostate cancer as measured by the Expanded Prostate Cancer Index Composite.

2015 ◽  
Vol 33 (7_suppl) ◽  
pp. 39-39
Author(s):  
Nicholas RIchard Cnossen ◽  
Amber Gail Orman ◽  
Deukwoo Kwon ◽  
Chad Ritch ◽  
Mark Gonzalgo ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Prostate Cancer ◽  
Radiation Therapy ◽  
Meta Analysis ◽  
Primary Treatment ◽  
Health Related Quality ◽  
Related Quality ◽  
Health Related

39 Background: Health-related quality of life (HRQoL) outcomes are important in treatment selection for prostate cancer. The Expanded Prostate Cancer Index Composite (EPIC) is a validated and widely-utilized HRQoL survey which accounts for newer radiotherapeutic, surgical, and hormonal treatment methods. We present a meta-analysis of patient reported HRQoL outcomes collected with EPIC and compare HRQoL trends with radiation therapy, surgery, or active surveillance as primary treatment. Methods: The PubMed database was systematically searched for all studies which presented data directly derived from the use of EPIC on patients with prostate cancer prior to 07/09/2014. All eligible studies were selected for either inclusion and analysis or exclusion based on pre-determined criteria. The data from included studies was compiled and a simulation-based estimation method using Approximate Bayesian Computation was performed to obtain missing standard deviation estimate. A longitudinal meta-analysis was conducted to estimate EPIC-profiles for each component using Bayesian p-spline method. Results: Over 4,000 studies were searched, 152 were deemed eligible, and 39 were included. The calculated mean summary score estimates are shown in the attached table. Conclusions: In the urinary domain, radical prostatectomy (RP) has lower acute scores than active surveillance (AS) or radiation therapy (RT) without long-term difference. In the bowel domain, RT has lower scores than AS or RP acutely and long-term. In the sexual domain, RT and RP have lower acute scores than AS. RP has lower scores than RT without long-term difference. In the hormonal domain, little difference was noted between modalities. [Table: see text]

Late rectal symptoms and quality of life after conformal radiation therapy for prostate cancer

2006 ◽  
Vol 79 (3) ◽  
pp. 341-347 ◽  
Author(s):  
Hans Geinitz ◽  
Frank B. Zimmermann ◽  
Reinhard Thamm ◽  
Caroline Erber ◽  
Tobias Müller ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Prostate Cancer ◽  
Radiation Therapy ◽  
Conformal Radiation Therapy
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