Determination of phenelzine in human plasma with gas chromatography—mass spectrometry using an isotope labeled internal standard

Author(s):  
Satya P. Jindal ◽  
Theresa Lutz ◽  
Thomas B. Cooper
1990 ◽  
Vol 73 (6) ◽  
pp. 883-886
Author(s):  
Susan S.C Tai ◽  
Nancy Cargile ◽  
Charlie J Barnes ◽  
Philip Kijak

Abstract During an evaluation of the gas chromatography/mass spectrometry (GC/MS) confirmatory procedure of Lynch and Bartoluccl for pyrantel residues in swine tissues, we developed a GC flame Ionization method for quantltatlng pyrantel residues In extracts of swine liver. The method was subjected to trial principally In the laboratories of Biospherics, Inc., using control liver, fortified control liver, and Incurred liver tissue samples. Although the method does not meet all of the current Food and Drug Administration criteria, it compares favorably to the official determinative method. Portions of the same extract can be used for quantitation and for GC/MS confirmation, true recoveries appear to be slightly higher, and an internal standard Is not required. The precision of this method equals or exceeds that of the official determinative method.


1995 ◽  
Vol 9 (1) ◽  
pp. 32-35 ◽  
Author(s):  
C. Lartigue-Mattei ◽  
M. J. Galmier ◽  
J. L. Chabard ◽  
E. Beyssac ◽  
J. M. Aiache

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