PERFORMANCE OF PRESTABILIZATION SHOCK INDEX AS A PREDICTOR OF MORTALITY IN PATIENTS ADMITTED WITH ST-SEGMENT ELEVATION MYOCARDIAL INFARCTION: THE ATHEROSCLEROSIS RISK IN COMMUNITIES SURVEILLANCE STUDY

2018 ◽  
Vol 71 (11) ◽  
pp. A239 ◽  
Author(s):  
Michael W. Chambers ◽  
Eric A. Whitsel ◽  
George Stouffer ◽  
Amil Shah ◽  
Melissa Caughey
2019 ◽  
Vol 10 (9) ◽  
pp. 1048-1055
Author(s):  
Sameer Arora ◽  
Matthew A Cavender ◽  
Patricia P Chang ◽  
Arman Qamar ◽  
Wayne D Rosamond ◽  
...  

Abstract Background The fourth universal definition of myocardial infarction requires an increase or decrease in cardiac troponin for the classification of non-ST-segment elevation myocardial infarction. We sought to determine whether the characteristics, management, and outcomes of patients admitted with non-ST-segment elevation myocardial infarction differ by the initial biomarker pattern. Methods We identified patients in the Atherosclerosis Risk in Communities Surveillance Study admitted with chest pain and an initially elevated cardiac troponin I, who presented within 12 hours of symptom onset and were classified with non-ST-segment elevation myocardial infarction. A change in cardiac troponin I required an absolute difference of at least 0.02 ng/mL on the first day of hospitalization, prior to invasive cardiac procedures. Results A total of 1926 hospitalizations met the inclusion criteria, with increasing cardiac troponin I more commonly observed (78%). Patients with decreasing cardiac troponin I were more often black (45% vs. 35%) and women (54% vs. 40%), and were less likely to receive non-aspirin antiplatelets (44% vs. 63%), lipid-lowering agents (62% vs. 80%), and invasive angiography (38% vs. 64%). Inhospital mortality was 3%, irrespective of the cardiac troponin I pattern. However, patients with decreasing cardiac troponin I had twice the 28-day mortality (12% vs. 5%; P=0.01). Fatalities within 28 days were more often attributable to non-cardiovascular causes in those with decreasing versus increasing cardiac troponin I (75% vs. 38%; P=0.01). Conclusion Patients presenting with chest pain and an initially elevated cardiac troponin I which subsequently decreases are less often managed by evidence-based therapies and have greater mortality, primarily driven by non-cardiovascular causes. Whether associations are attributable to type 2 myocardial infarction or a subacute presentation merits further investigation.


2018 ◽  
Vol 37 (6) ◽  
pp. 481-488
Author(s):  
Glória Abreu ◽  
Pedro Azevedo ◽  
Carlos Galvão Braga ◽  
Catarina Vieira ◽  
Miguel Álvares Pereira ◽  
...  

2021 ◽  
Vol 49 (3) ◽  
pp. 030006052110005
Author(s):  
Guoyu Wang ◽  
Ruzhu Wang ◽  
Ling Liu ◽  
Jing Wang ◽  
Lei Zhou

Objective We aimed to determine whether the prognostic value of the shock index (SI) and its derivatives is better than that of the Thrombolysis In Myocardial Infarction risk index (TRI) for predicting adverse outcomes in patients with ST-segment elevation myocardial infarction (STEMI) undergoing primary percutaneous coronary intervention (PCI). Methods A total of 257 patients with STEMI undergoing primary PCI from January 2018 to June 2019 were analyzed in a retrospective cohort study. The SI, modified shock index (MSI), age SI (age × the SI), age MSI (age × the MSI), and TRI at admission were calculated. Clinical endpoints were in-hospital complications, including all-cause mortality, acute heart failure, cardiac shock, mechanical complications, re-infarction, and life-threatening arrhythmia. Results Multivariate analyses showed that a high SI, MSI, age SI, age MSI, and TRI at admission were associated with a significantly higher rate of in-hospital complications. The predictive value of the age SI and age MSI was comparable with that of the TRI (area under the receiver operating characteristic curve: z = 1.313 and z = 0.882, respectively) for predicting in-hospital complications. Conclusions The age SI and age MSI appear to be similar to the TRI for predicting in-hospital complications in patients with STEMI undergoing primary PCI.


2019 ◽  
Vol 30 (8) ◽  
pp. 575-583
Author(s):  
Gjin Ndrepepa ◽  
Salvatore Cassese ◽  
Erion Xhepa ◽  
Massimiliano Fusaro ◽  
Karl-Ludwig Laugwitz ◽  
...  

Sign in / Sign up

Export Citation Format

Share Document