THE NOVEL USE OF INTRACARDIAC ECHOCARDIOGRAPHY FOR HEMODYNAMIC ASSESSMENT DURING INVASIVE LEFT VENTRICULAR ASSIST DEVICE RAMP STUDIES

2018 ◽  
Vol 71 (11) ◽  
pp. A747
Author(s):  
Andrew Rosenbaum ◽  
Mahwash Kassi ◽  
Brandon Wiley ◽  
Atta Behfar
2021 ◽  
Vol 11 (1) ◽  
Author(s):  
Konstantin Yastrebov ◽  
Laurencie Brunel ◽  
Hugh S. Paterson ◽  
Zoe A. Williams ◽  
Innes K. Wise ◽  
...  

An amendment to this paper has been published and can be accessed via a link at the top of the paper.


Medicina ◽  
2022 ◽  
Vol 58 (1) ◽  
pp. 116
Author(s):  
Gassan Moady ◽  
Tuvia Ben Gal ◽  
Shaul Atar

The novel coronavirus disease 2019 (COVID-19) is an infectious disease with multi-organ involvement, including the cardiovascular system. The disease may cause several cardiovascular complications, and may increase morbidity and mortality among patients with background cardiovascular disease. Patients with advanced heart failure are often treated with left ventricular assist device (LVAD), and represent a unique population mandating multi-disciplinary approach. Several aspects of COVID-19 should be taken into account in LVAD implants, including right ventricular involvement, hemodynamic alterations, thromboembolic and haemorrhagic complications, and the psychological effects of social isolation. Patients with VAD and suspected COVID-19 should be transferred to specialized centers for better management of complications. Here, we review the implications of COVID-19 pandemic on LVAD patients with our recommendations for appropriate management.


Author(s):  
Dmitry Telyshev ◽  
Alexander Pugovkin ◽  
Ivan Ephimov ◽  
Aleksandr Markov ◽  
Steffen Leonhardt ◽  
...  

In this paper, we aim to assess the electric current parameters and report the analysis of the associated degree of ventricular recovery during left ventricular assist device (LVAD) support. An assumption was made there is a linear relationship between ventricular recovery degree and the pump electric current pulsatility index (PI). The experimental study was carried out using the ViVitro Pulse Duplicator System with Sputnik 1 LVAD connected. Cardiac output (CO) and cardiac power output (CPO) were used as a measure of ventricular recovery degree. Different heart rates (HR) (59, 73, 86 bpm) and pump speeds (7600–8400 rpm in 200 rpm steps) were investigated. Ventricular stroke volumes in the range of 30–80 ml for each heart rate at certain pump speed were used. The obtained relationships of CO and CPO vs. PI was linear as the coefficients of determination for each regression curve were more than 0.8. CO vs. PI: R2=0.9218; 0.9271; 0.9172 and CPO vs. PI: R2=0.8517; 0.841; 0.8244 for HR=59 bpm; 73 bpm; 86 bpm, respectively. Study findings suggest that adequate interpretation of parameters could potentially serve as a valuable clinical tool to assess ventricular recovery based on LVAD infrastructure without requiring any special hemodynamic assessment.


Medicina ◽  
2020 ◽  
Vol 56 (8) ◽  
pp. 413
Author(s):  
Teruhiko Imamura ◽  
Nikhil Narang

Durable left ventricular assist device therapy has improved survival in patients with advanced heart failure refractory to conventional medical therapy, although the readmission rates due to device-related comorbidities remain high. Left ventricular assist devices are designed to support a failing left ventricle through relief of congestion and improvement of cardiac output. However, many patients still have abnormal hemodynamics even though they may appear to be clinically stable. Furthermore, such abnormal hemodynamics are associated with an increased risk of future adverse events including recurrent heart failure, gastrointestinal bleeding, stroke, and pump thrombosis. Correction of residual hemodynamic derangements post-implantation may be a target in improving longitudinal clinical outcomes during left ventricular assist device support. Automatic and timely device speed adjustments considering a patients’ hemodynamic status (i.e., with a smart pump) are potential improvements in forthcoming devices.


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