The vacuolar ATPase subunit E controls apoptosis and is up-regulated in breast cancer

2016 ◽  
Vol 61 ◽  
pp. S80-S81
Author(s):  
S.N. Mohammed ◽  
M. Mourtada-Maarabouni
Keyword(s):  
Breast Cancer ◽  
Vacuolar Atpase ◽  
Atpase Subunit ◽  
Subunit E

scholarly journals Apoptosis Gene Hunting Using Retroviral Expression Cloning: Identification of Vacuolar ATPase Subunit E

2003 ◽  
Vol 3 ◽  
pp. 51-58 ◽  
Author(s):  
Claire L. Anderson ◽  
Gwyn T. Williams
Keyword(s):  
Research Effort ◽  
Regulatory Gene ◽  
Vacuolar Atpase ◽  
Expression Cloning ◽  
Isolation And Identification ◽  
Atpase Subunit ◽  
Subunit E ◽  
Cloning Strategy ◽  
Apoptosis Gene ◽  
Gene Hunting

Over the past 10-15 years there has been an explosion of interest in apoptosis. The delayed realisation that cell death is an essential part of life for any multicellular organism has meant that, despite the recent and rapid developments of the last decade, the precise biochemical pathways involved in apoptosis remain incomplete and potentially novel genes may, as yet, remain undiscovered. The hunt is therefore on to bridge the remaining gaps in our knowledge. Our contribution to this research effort utilises a functional cloning approach to isolate important regulatory genes involved in apoptosis. This mini-review focuses on the use and advantages of a retroviral expression cloning strategy and describes the isolation and identification of one such potential apoptosis regulatory gene, namely that encoding vacuolar ATPase subunit E.

Abstract 464: Tumor derived vacuolar ATPase subunit promotes M2 type polarization of macrophages.

2013 ◽  
Author(s):  
Gajendra K. Katara ◽  
Mukesh K. Jaiswal ◽  
Alice Gilmam-Sacks ◽  
Kenneth D. Beaman
Keyword(s):  
Vacuolar Atpase ◽  
Atpase Subunit

Cloning, sequencing and expression of cDNA encoding an insect V-ATPase subunit E

1994 ◽  
Vol 1190 (1) ◽  
pp. 193-196 ◽  
Author(s):  
Ralph Gräf ◽  
William R. Harvey ◽  
Helmut Wieczorek
Keyword(s):  
Atpase Subunit ◽  
Subunit E ◽  
Sequencing And Expression

Arabidopsis vacuolar H+-ATPase subunit E isoform 1 is required for Golgi organization and vacuole function in embryogenesis

2004 ◽  
Vol 41 (1) ◽  
pp. 125-132 ◽  
Author(s):  
Georg Strompen ◽  
Jan Dettmer ◽  
York-Dieter Stierhof ◽  
Karin Schumacher ◽  
Gerd Jürgens ◽  
...  
Keyword(s):  
Atpase Subunit ◽  
Subunit E ◽  
Golgi Organization

Expression, purification, and characterization of subunit E, an essential subunit of the vacuolar ATPase

2002 ◽  
Vol 298 (3) ◽  
pp. 383-391 ◽  
Author(s):  
Gerhard Grüber ◽  
Jasminka Godovac-Zimmermann ◽  
Thomas A Link ◽  
Ünal Coskun ◽  
Vincenzo F Rizzo ◽  
...  
Keyword(s):  
Vacuolar Atpase ◽  
Purification And Characterization ◽  
Subunit E ◽  
Essential Subunit

scholarly journals Breast cancer associated a2 isoform vacuolar ATPase immunomodulates neutrophils: potential role in tumor progression

Oncotarget ◽  
2015 ◽  
Vol 6 (32) ◽  
pp. 33033-33045 ◽  
Author(s):  
Safaa A. Ibrahim ◽  
Gajendra K. Katara ◽  
Arpita Kulshrestha ◽  
Mukesh K. Jaiswal ◽  
Magdy A. Amin ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Tumor Progression ◽  
Potential Role ◽  
Vacuolar Atpase
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