Health-related quality of life after radical cystectomy for bladder cancer: a comparison of ileal conduit and orthotopic bladder replacement.

2003 ◽  
Vol 21 (2) ◽  
pp. 167 ◽  
Author(s):  
I Hara ◽  
H Miyake ◽  
S Hara ◽  
A Gotoh ◽  
I Nakamura ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Bladder Cancer ◽  
Radical Cystectomy ◽  
Ileal Conduit ◽  
Health Related Quality ◽  
Bladder Replacement ◽  
Related Quality ◽  
Health Related

scholarly journals Health-related quality of life in bladder cancer patients undergoing radical cystectomy and urinary stoma: still many gaps

2018 ◽  
Vol 7 (S1) ◽  
pp. S111-S113
Author(s):  
Massimiliano Creta ◽  
Nicola Longo ◽  
Ciro Imbimbo ◽  
Vittorio Imperatore ◽  
Vincenzo Mirone ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Bladder Cancer ◽  
Cancer Patients ◽  
Radical Cystectomy ◽  
Health Related Quality ◽  
Related Quality ◽  
Health Related

Does robotic radical cystectomy for bladder cancer affect long-term health-related quality of life?

2010 ◽  
Vol 211 (3) ◽  
pp. S134
Author(s):  
Matthew Raynor ◽  
Stephen McKim ◽  
Euugene Simopolous ◽  
Matthew Nielsen ◽  
Eric Wallen ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Bladder Cancer ◽  
Radical Cystectomy ◽  
Health Related Quality ◽  
Related Quality ◽  
Health Related ◽  
Robotic Radical Cystectomy

scholarly journals Effect of neoadjuvant chemotherapy on health-related quality of life in patients with muscle-invasive bladder cancer: results from JCOG0209, a randomized phase III study

2020 ◽  
Vol 50 (12) ◽  
pp. 1464-1469
Author(s):  
Hiroshi Kitamura ◽  
Shiro Hinotsu ◽  
Taiji Tsukamoto ◽  
Taro Shibata ◽  
Junki Mizusawa ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Bladder Cancer ◽  
Neoadjuvant Chemotherapy ◽  
Radical Cystectomy ◽  
Health Related Quality ◽  
Muscle Invasive Bladder Cancer ◽  
Related Quality ◽  
Health Related ◽  
Muscle Invasive

Abstract Background Although neoadjuvant chemotherapy provides survival benefits in muscle-invasive bladder cancer, the impact of neoadjuvant chemotherapy on health-related quality of life has not been investigated by a randomized trial. The purpose of this study is to compare health-related quality of life in patients with muscle-invasive bladder cancer who received neoadjuvant chemotherapy followed by radical cystectomy or radical cystectomy alone based on patient-reported outcome data. Methods Patients were randomized to receive two cycles of neoadjuvant methotrexate, doxorubicin, vinblastine, and cisplatin followed by radical cystectomy or radical cystectomy alone. Health-related quality of life was measured using the Functional Assessment of Cancer Therapy-Bladder (version 4) questionnaire before the protocol treatments, after neoadjuvant chemotherapy, after radical cystectomy and 1 year after registration. Results A total of 99 patients were analysed. No statistically significant differences in postoperative health-related quality of life were found between the arms. In the neoadjuvant chemotherapy arm, the scores after neoadjuvant chemotherapy were significantly lower than the baseline scores in physical well-being, functional well-being, Functional Assessment of Cancer Therapy-General total, weight loss, diarrhoea, appetite, body appearance, embarrassment by ostomy appliance and total Functional Assessment of Cancer Therapy-Bladder. However, there was no difference in scores for these domains, except for embarrassment by ostomy appliance, between the two arms after radical cystectomy and 1 year after registration. Conclusions Although health-related quality of life declined during neoadjuvant chemotherapy, no negative effect of neoadjuvant chemotherapy on health-related quality of life was apparent after radical cystectomy. These data support the view that neoadjuvant chemotherapy can be considered as a standard of care for patients with muscle-invasive bladder cancer regarding health-related quality of life.

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