:
Conventional drug discovery is a time overwhelming and expensive expedition with super less clinical
preference achievement proportion intended for breast cancer therapy. Even if numerous novel approaches to the
conformation of drugs have been introduced for breast cancer therapy, they have up till now to be implemented in clinical
practice. This tempting strategy, facilitate a remarkable chance to take the entire benefit of existing drugs. Despite drug
repurposing significantly decrease the investigational period and cost, it has got many objections and issues. Scaffold
repurposing is the approach that procures a novel significance on the decrepit motto of “to commencement with a
pristine drug” Hence, ourselves move into a probable and nearer approach, the exploitation of scaffolds originally
developed for other purposes as well anti-tumour activity. In this review, we summarize the different drugs and scaffolds
used in breast cancer therapy.