scholarly journals Correlation Between Quadrant Specific Automatic Visual Field Defect and Retinal Nerve Fiber Layer Thickness as Measured by Scanning Laser Polarimetry in Patients With Primary Open Angle Glaucoma

2008 ◽  
Vol 24 (5) ◽  
pp. 233-239
Author(s):  
Yo-Chen Chang ◽  
Rong-Kung Tsai
2013 ◽  
Vol 54 (12) ◽  
pp. 7739 ◽  
Author(s):  
Kenya Yuki ◽  
Sachiko Tanabe ◽  
Keisuke Kouyama ◽  
Kazumi Fukagawa ◽  
Miki Uchino ◽  
...  

2021 ◽  
Vol 8 ◽  
Author(s):  
Jingyi Cheng ◽  
Hongmei Zhao ◽  
Chunhui Jiang ◽  
Xiangmei Kong ◽  
Xinghuai Sun

Purpose: To investigate the changes in the retinal vessels (RVs) in different sectors in patients with primary open-angle glaucoma (POAG), and their possible correlations with retinal nerve fiber layer thickness (RNFLT) and visual-field defects in the temporal parapapillary region.Methods: The RV diameters, RNFLTs, and visual-field parameters were measured. The temporal parapapillary region was divided into the temporal (T, 315°-45°), temporal superior (TS, 45°-90°), and temporal inferior sectors (TI, 270°-315°). The changes in the RV diameters in each sector were determined, and their relationships with RNFLT, the mean deviation (MD), and visual field sensitivity (VFS) were examined.Results: Fifty POAG patients (50 eyes) and 50 healthy subjects (50 eyes) were included. Compared with the healthy subjects, the POAG group had a significantly smaller accumulated parapapillary RV diameter (P < 0.001), which was positively correlated with the MD and RNFLT. When the different temporal sectors were examined, the accumulated RV diameters were significantly smaller in the POAG group than in the healthy controls in the TI and T sectors, but not in the TS sector. The accumulated diameters in the TI and T sectors were correlated with the corresponding RNFLTs (all P < 0.05), but only the accumulated diameter in the TI sector was correlated with the VFS.Conclusions: In POAG, the changes in the RVs differed between different temporal sectors, with the most prominent changes occurring in the TI and T sectors.


2015 ◽  
pp. 2217 ◽  
Author(s):  
Tomoko Naito ◽  
Keiji Yoshikawa ◽  
Shiro Mizoue ◽  
Mami Nanno ◽  
Tairo Kimura ◽  
...  

2020 ◽  
pp. 112067212095758
Author(s):  
Sebastião Cronemberger ◽  
Artur W Veloso ◽  
Christy Veiga ◽  
Gustavo Scarpelli ◽  
Yara C Sasso ◽  
...  

Purpose: To analyze the relationship between retinal nerve fiber layer thickness (RNFLT) and intraocular pressure (IOP) variation in glaucoma suspects (GS) and patients with primary open-angle glaucoma (POAG). Methods: Thirty-one GS and 34 POAG patients underwent ophthalmologic examination and 24-h IOP measurements. GS had IOPs ranging from 19 to 24 mmHg and/or suspicious appearance of the optic nerve. POAG patients had reproducible abnormal visual fields. We only included patients who presented with short-term IOP fluctuation >6 mm Hg (∆IOP). Only one eye per patient was included through a randomized process. Peripapillary RNFLT was assessed by spectral-domain optical coherence tomography. We correlated RNFLT with IOP parameters. Results: Mean IOP was similar between GS and POAG groups (15.6 ± 3.47 vs 15.6 ± 2.83 mmHg, p = 0.90) as was IOP peak at 6 AM (21.7 ± 3.85 vs 21.3 ± 3.80 mmHg, p = 0.68). Statistically significant negative correlations were found in POAG group between IOP at 6 AM and RNFLT in global ( rs = −0.543; p < 0.001), inferior ( rs = −0.540; p < 0.001), superior ( rs = −0.405; p = 0.009), and nasal quadrants ( rs = −0.561; p < 0.001). Negative correlations were also found between ∆IOP and RNFLT in global ( rs = −0.591; p < 0.001), and all other sectors ( p < 0.05). In GS IOP at 6 AM correlated only with inferior quadrant ( rs = −0.307; p = 0.047). Conclusion: IOP at 6 AM and ∆IOP had negative correlations with RNFLT quadrants in POAG. In GS this correlation occurred between IOP at 6 AM and inferior quadrant. These findings may indicate potential risk factors for glaucoma progression.


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