Computational fluid dynamics (CFD) and direct visualization studies of aerosol release from two cyclohaler-type dry powder inhalers

2012 ◽  
Vol 22 (2) ◽  
pp. 161-165 ◽  
Author(s):  
A. Moskal ◽  
T.R. Sosnowski
Author(s):  
David F Fletcher ◽  
Vishal Chaugule ◽  
Larissa Gomes dos Reis ◽  
Paul M Young ◽  
Daniela Traini ◽  
...  

1996 ◽  
Vol 33 (9) ◽  
pp. 163-170 ◽  
Author(s):  
Virginia R. Stovin ◽  
Adrian J. Saul

Research was undertaken in order to identify possible methodologies for the prediction of sedimentation in storage chambers based on computational fluid dynamics (CFD). The Fluent CFD software was used to establish a numerical model of the flow field, on which further analysis was undertaken. Sedimentation was estimated from the simulated flow fields by two different methods. The first approach used the simulation to predict the bed shear stress distribution, with deposition being assumed for areas where the bed shear stress fell below a critical value (τcd). The value of τcd had previously been determined in the laboratory. Efficiency was then calculated as a function of the proportion of the chamber bed for which deposition had been predicted. The second method used the particle tracking facility in Fluent and efficiency was calculated from the proportion of particles that remained within the chamber. The results from the two techniques for efficiency are compared to data collected in a laboratory chamber. Three further simulations were then undertaken in order to investigate the influence of length to breadth ratio on chamber performance. The methodology presented here could be applied to complex geometries and full scale installations.


2021 ◽  
Vol 54 ◽  
pp. 102207
Author(s):  
Cristian Inostroza ◽  
Alessandro Solimeno ◽  
Joan García ◽  
José M. Fernández-Sevilla ◽  
F. Gabriel Acién

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