Solubility Behavior of l-Homophenylalanine Ethyl Ester Hydrochloride in 12 Individual Solvents from 283.15 to 323.15 K

Author(s):  
Ying Guo ◽  
Hui He ◽  
Haishuang Huang ◽  
Jingxuan Qiu ◽  
Jiaming Han ◽  
...  
1970 ◽  
Vol 48 (16) ◽  
pp. 2509-2511 ◽  
Author(s):  
Brian J. Johnson ◽  
Donna S. Rea

The synthesis of the tetrapeptide, N-t-butoxycarbonyl-ε-N-carbobenzoxy-L-lysylglycyl-ε-N-carbobenzoxy-L-lysylglycine 4-(methylthio)phenyl ester is described. The utility of this protective ester is shown by its easy conversion to the protected tetrapeptide 4-(methylsulfonyl)phenyl activated ester without decomposition. Removal of the N-butoxycarbonyl protecting group afforded the polymerizing unit, ε-N-carbobenzoxy-L-lysylglycyl-ε-N-carbobenzoxy-L-lysylglycine 4-(methylsulfonyl)phenyl ester. Polymerization of this material on the partially blocked monomer glycine-1-C14 ethyl ester hydrochloride, at a relatively high dilution, gave poly-(ε-N-carbobenzoxyl-L-lysylglycyl)glycine-1-C14 ethyl ester. The carbobenzoxy protective groups were removed to give the title compound.


2012 ◽  
Vol 14 (8) ◽  
pp. 2162-2163 ◽  
Author(s):  
Bill Morandi ◽  
Amund Dolva ◽  
E. M. Carreira

2013 ◽  
Vol 117 (51) ◽  
pp. 14243-14252 ◽  
Author(s):  
M. E. Defonsi Lestard ◽  
S. B. Díaz ◽  
M. Puiatti ◽  
G. A. Echeverría ◽  
O. E. Piro ◽  
...  

Molbank ◽  
10.3390/m1166 ◽  
2020 ◽  
Vol 2020 (4) ◽  
pp. M1166
Author(s):  
Mario Leyva-Acuña ◽  
Francisco Delgado-Vargas ◽  
Gabriela López-Angulo ◽  
Julio Montes-Avila

Pyrimidines are compounds with a wide range of biological activities, and the synthesis of pyrimidine derivatives—useful in chemical and medicinal applications—is important in medicinal chemistry. This work shows the synthesis under microwave irradiation of the novel compound ethyl (S)-2-benzamido-5-[(4,6-dimethylpyrimidin-2-yl)amino]pentanoate (3) from (S)-N-α-benzoyl-l-arginine ethyl ester hydrochloride (1) and acetylacetone (2). Compound 3 was easily purified, obtained in moderate yield (70%), and fully characterized by UV-Vis, FTIR-ATR spectroscopy, 1H-NMR, 13C-NMR, HRMS, and EI-MS.


1988 ◽  
Vol 52 (10) ◽  
pp. 2679-2681 ◽  
Author(s):  
Yoshihiro KAWASAKI ◽  
Takashi SEKI ◽  
Masahiro TAMURA ◽  
Eiichi KIKUCHI ◽  
Makoto TADA ◽  
...  

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