Design, Synthesis, and Biological Evaluation of a Novel Series of Teriflunomide Derivatives as Potent Human Dihydroorotate Dehydrogenase Inhibitors for Malignancy Treatment

Design, synthesis, and biological evaluation of novel substituted benzamide derivatives bearing a 1,2,3-triazole moiety as potent human dihydroorotate dehydrogenase inhibitors

Bioorganic Chemistry ◽

10.1016/j.bioorg.2017.12.025 ◽

2018 ◽

Vol 76 ◽

pp. 528-537 ◽

Cited By ~ 5

Author(s):

Kuan Lu ◽

Lude Cai ◽

Xue Zhang ◽

Guodong Wu ◽

Congjun Xu ◽

...

Keyword(s):

Biological Evaluation ◽

Dihydroorotate Dehydrogenase ◽

Design Synthesis ◽

Substituted Benzamide ◽

Synthesis And Biological Evaluation ◽

Benzamide Derivatives

Design, Synthesis, and Biological Evaluation of 4-Quinoline Carboxylic Acids as Inhibitors of Dihydroorotate Dehydrogenase

Journal of Medicinal Chemistry ◽

10.1021/acs.jmedchem.7b01862 ◽

2018 ◽

Vol 61 (12) ◽

pp. 5162-5186 ◽

Cited By ~ 18

Author(s):

Joseph T. Madak ◽

Christine R. Cuthbertson ◽

Yoshinari Miyata ◽

Shuzo Tamura ◽

Elyse M. Petrunak ◽

...

Keyword(s):

Carboxylic Acids ◽

Biological Evaluation ◽

Dihydroorotate Dehydrogenase ◽

Design Synthesis ◽

Design, Synthesis and Biological Evaluation of some Chalcone Derivatives as Potential Pancreatic Lipase Inhibitors

10.3390/ecsoc-17-b024 ◽

2013 ◽

Author(s):

Dao Tran

Keyword(s):

Pancreatic Lipase ◽

Biological Evaluation ◽

Design Synthesis ◽

Chalcone Derivatives ◽

Pancreatic Lipase Inhibitors ◽

Faculty Opinions recommendation of Structure-Based Design, Synthesis, and Biological Evaluation of Highly Selective and Potent G Protein-Coupled Receptor Kinase 2 Inhibitors.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.726271231.793520213 ◽

2016 ◽

Author(s):

Miles Congreve ◽

Mark Pickworth

Keyword(s):

G Protein ◽

Biological Evaluation ◽

Receptor Kinase ◽

G Protein Coupled Receptor ◽

Design Synthesis ◽

G Protein Coupled ◽

Design, Synthesis and Biological Evaluation of Hybrid Molecules Containing Conjugated Styryl Ketone and α-Bromoacryloyl Moieties

10.2174/157018012799079842 ◽

2012 ◽

Vol 9 (2) ◽

pp. 140-152 ◽

Cited By ~ 1

Author(s):

Romeo Romagnoli ◽

Pier Giovanni Baraldi ◽

Olga Cruz-Lopez ◽

Maria Kimatrai Salvador ◽

Delia Preti ◽

...

Keyword(s):

Biological Evaluation ◽

Design Synthesis ◽

Hybrid Molecules ◽

Design, Synthesis and Biological Evaluation of Novel Aminosaccharide Derivatives of Combretastatin A-4

10.2174/15701808113109990024 ◽

2013 ◽

Vol 10 (10) ◽

pp. 935-941

Author(s):

Yan Tang ◽

Zhewei Tu ◽

Jing Sun ◽

Xiong Zhu ◽

Kun Liu ◽

...

Keyword(s):

Biological Evaluation ◽

Design Synthesis ◽

Synthesis And Biological Evaluation ◽

Derivatives Of

Design, Synthesis and Biological Evaluation of Some Oxadiazole Derivatives as Novel Amide-Based Inhibitors of Soluble Epoxide Hydrolase

10.2174/1570180811666140220005530 ◽

2014 ◽

Vol 11 (6) ◽

pp. 721-730 ◽

Cited By ~ 8

Author(s):

Elham Zavareh ◽

Mahdi Hedayati ◽

Laleh Rad ◽

Azin Kiani ◽

Soraya Shahhosseini ◽

...

Keyword(s):

Epoxide Hydrolase ◽

Soluble Epoxide Hydrolase ◽

Biological Evaluation ◽

Design Synthesis ◽

Oxadiazole Derivatives ◽

Rational Design, Synthesis and Biological Evaluation of Novel Derivatives Based on in vivo Metabolism of Natural Product β-elemene

10.2174/1570180814666171108093021 ◽

2018 ◽

Vol 15 (8) ◽

pp. 905-912 ◽

Cited By ~ 1

Author(s):

Renren Bai ◽

Xiaokang Jie ◽

Eric Salgado ◽

Jian Sun ◽

Yao Zhu ◽

...

Keyword(s):

Natural Product ◽

Rational Design ◽

Biological Evaluation ◽

In Vivo Metabolism ◽

Design Synthesis ◽

Design, Synthesis and Biological Evaluation of Benzopyran Derivatives as KATP Channel Openers

10.2174/157018010791306560 ◽

2010 ◽

Vol 7 (6) ◽

pp. 415-420 ◽

Cited By ~ 3

Author(s):

Jinpei Zhou ◽

Hai Qian ◽

Huibin Zhang ◽

Hui Gao ◽

Wenlong Huang ◽

...

Keyword(s):

Katp Channel ◽

Biological Evaluation ◽

Design Synthesis ◽

Synthesis And Biological Evaluation ◽

Katp Channel Openers

Design, Synthesis and Biological Evaluation of Novel Fluorinated Heterocyclic Hybrid Molecules Based on Triazole & Quinoxaline Scaffolds Lead to Highly Potent Antimalarials and Antibacterials

10.2174/1570180812666141111235301 ◽

2015 ◽

Vol 12 (5) ◽

pp. 393-407 ◽

Cited By ~ 6

Author(s):

Adimulam Shekhar ◽

Boddupally Lingaiah ◽

Pamulaparthy Rao ◽

Banda Narsaiah ◽

Aparna Allanki ◽

...

Keyword(s):

Biological Evaluation ◽

Design Synthesis ◽

Hybrid Molecules ◽