Design, Synthesis and Biological Evaluation of Some Oxadiazole Derivatives as Novel Amide-Based Inhibitors of Soluble Epoxide Hydrolase

2014 ◽  
Vol 11 (6) ◽  
pp. 721-730 ◽  
Author(s):  
Elham Zavareh ◽  
Mahdi Hedayati ◽  
Laleh Rad ◽  
Azin Kiani ◽  
Soraya Shahhosseini ◽  
...  
Keyword(s):  
Epoxide Hydrolase ◽  
Soluble Epoxide Hydrolase ◽  
Biological Evaluation ◽  
Design Synthesis ◽  
Oxadiazole Derivatives ◽  
Synthesis And Biological Evaluation

Novel soluble epoxide hydrolase inhibitors with a dihydropyrimidinone scaffold: design, synthesis and biological evaluation

MedChemComm ◽  
2016 ◽  
Vol 7 (11) ◽  
pp. 2128-2135 ◽  
Author(s):  
Elham Rezaee ◽  
Mahdi Hedayati ◽  
Laleh Hoghooghi Rad ◽  
Soraya Shahhosseini ◽  
Mehrdad Faizi ◽  
...  
Keyword(s):  
Epoxide Hydrolase ◽  
Soluble Epoxide Hydrolase ◽  
Biological Evaluation ◽  
Scaffold Design ◽  
Urea Derivatives ◽  
Design Synthesis ◽  
Soluble Epoxide Hydrolase Inhibitors ◽  
Synthesis And Biological Evaluation

Amide non-urea derivatives with a dihydropyrimidinone ring as a novel secondary pharmacophore against the sEH enzyme were designed, synthesized and biologically evaluated.

scholarly journals Synthesis and biological evaluation of soluble epoxide hydrolase (sEH) inhibitors: t‐AUCB and its derivatives

2008 ◽  
Vol 22 (S1) ◽  
Author(s):  
SUNG HEE HWANG ◽  
Hsing‐Ju Tsai ◽  
Christophe Morisseau ◽  
Jun‐Yan Liu ◽  
Bruce D. Hammock
Keyword(s):  
Epoxide Hydrolase ◽  
Soluble Epoxide Hydrolase ◽  
Biological Evaluation ◽  
Synthesis And Biological Evaluation

Design, Synthesis, and Biological Evaluation of 2‐(2‐Bromo‐3‐nitrophenyl)‐5‐phenyl‐1,3,4‐oxadiazole Derivatives as Possible Anti‐Breast Cancer Agents

2020 ◽  
Vol 17 (2) ◽  
Author(s):  
Arjun H. Ananth ◽  
Natarajan Manikandan ◽  
Ravi Kumar Rajan ◽  
Ramakrishnan Elancheran ◽  
Kunasekaran Lakshmithendral ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Biological Evaluation ◽  
Design Synthesis ◽  
Oxadiazole Derivatives ◽  
Synthesis And Biological Evaluation

Design, synthesis and biological evaluation of 1,3,4-oxadiazole derivatives

2010 ◽  
Vol 45 (11) ◽  
pp. 4963-4967 ◽  
Author(s):  
Keshari Kishore Jha ◽  
Abdul Samad ◽  
Yatendra Kumar ◽  
Mohd. Shaharyar ◽  
Ratan Lal Khosa ◽  
...  
Keyword(s):  
Biological Evaluation ◽  
Design Synthesis ◽  
Oxadiazole Derivatives ◽  
Synthesis And Biological Evaluation
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