The Influence of the Strength of Drug–Polymer Interactions on the Dissolution of Amorphous Solid Dispersions

Molecular Pharmaceutics ◽

10.1021/acs.molpharmaceut.0c00790 ◽

2020 ◽

Vol 18 (1) ◽

pp. 174-186

Author(s):

Kweku K. Amponsah-Efah ◽

Pinal Mistry ◽

Reed Eisenhart ◽

Raj Suryanarayanan

Keyword(s):

Solid Dispersions ◽

Amorphous Solid ◽

Amorphous Solid Dispersions ◽

Polymer Interactions

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Hot Melt Extrusion for Amorphous Solid Dispersions: Temperature and Moisture Activated Drug–Polymer Interactions for Enhanced Stability

Molecular Pharmaceutics ◽

10.1021/mp400165b ◽

2013 ◽

Vol 10 (10) ◽

pp. 3665-3675 ◽

Author(s):

Ashish L. Sarode ◽

Harpreet Sandhu ◽

Navnit Shah ◽

Waseem Malick ◽

Hossein Zia

Keyword(s):

Solid Dispersions ◽

Amorphous Solid ◽

Hot Melt Extrusion ◽

Melt Extrusion ◽

Amorphous Solid Dispersions ◽

Polymer Interactions ◽

Hot Melt ◽

Enhanced Stability

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Balancing Solid-State Stability and Dissolution Performance of Lumefantrine Amorphous Solid Dispersions: The Role of Polymer Choice and Drug–Polymer Interactions

Molecular Pharmaceutics ◽

10.1021/acs.molpharmaceut.1c00481 ◽

2021 ◽

Author(s):

Tze Ning Hiew ◽

Dmitry Y. Zemlyanov ◽

Lynne S. Taylor

Keyword(s):

Solid State ◽

Solid Dispersions ◽

Amorphous Solid ◽

Amorphous Solid Dispersions ◽

Solid State Stability ◽

Polymer Interactions

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Miniaturized Measurement of Drug–Polymer Interactions via Viscosity Increase for Polymer Selection in Amorphous Solid Dispersions

Molecular Pharmaceutics ◽

10.1021/acs.molpharmaceut.9b00186 ◽

2019 ◽

Vol 16 (5) ◽

pp. 2214-2225 ◽

Author(s):

Carolin Auch ◽

Meike Harms ◽

Yury Golitsyn ◽

Detlef Reichert ◽

Karsten Mäder

Keyword(s):

Solid Dispersions ◽

Amorphous Solid ◽

Amorphous Solid Dispersions ◽

Viscosity Increase ◽

Polymer Interactions

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Hot melt extrusion (HME) for amorphous solid dispersions: Predictive tools for processing and impact of drug–polymer interactions on supersaturation

European Journal of Pharmaceutical Sciences ◽

10.1016/j.ejps.2012.12.012 ◽

2013 ◽

Vol 48 (3) ◽

pp. 371-384 ◽

Author(s):

Ashish L. Sarode ◽

Harpreet Sandhu ◽

Navnit Shah ◽

Waseem Malick ◽

Hossein Zia

Keyword(s):

Solid Dispersions ◽

Amorphous Solid ◽

Hot Melt Extrusion ◽

Melt Extrusion ◽

Amorphous Solid Dispersions ◽

Predictive Tools ◽

Polymer Interactions ◽

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Drug–Polymer Interactions in Acetaminophen/Hydroxypropylmethylcellulose Acetyl Succinate Amorphous Solid Dispersions Revealed by Multidimensional Multinuclear Solid-State NMR Spectroscopy

Molecular Pharmaceutics ◽

10.1021/acs.molpharmaceut.1c00427 ◽

2021 ◽

Author(s):

Andrea Pugliese ◽

Michael Toresco ◽

Daniel McNamara ◽

Dinu Iuga ◽

Anuji Abraham ◽

...

Keyword(s):

Solid State ◽

Nmr Spectroscopy ◽

Solid State Nmr ◽

Solid Dispersions ◽

Amorphous Solid ◽

Amorphous Solid Dispersions ◽

Solid State Nmr Spectroscopy ◽

Polymer Interactions

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Phase Behavior of Amorphous Solid Dispersions of Felodipine: Homogeneity and Drug–Polymer Interactions

Molecular Pharmaceutics ◽

10.1021/acs.molpharmaceut.9b00731 ◽

2019 ◽

Vol 16 (12) ◽

pp. 4836-4851 ◽

Author(s):

Kanika Sarpal ◽

Sean Delaney ◽

Geoff G. Z. Zhang ◽

Eric J. Munson

Keyword(s):

Phase Behavior ◽

Solid Dispersions ◽

Amorphous Solid ◽

Amorphous Solid Dispersions ◽

Polymer Interactions

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Molecular Mobility as a Polymer Selection Tool for Amorphous Solid Dispersions

10.26226/morressier.57d6b2b6d462b8028d88e3c5 ◽

2016 ◽

Author(s):

Pinal Mistry

Keyword(s):

Molecular Mobility ◽

Solid Dispersions ◽

Amorphous Solid ◽

Amorphous Solid Dispersions ◽

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Drug Dissolution Enhancement via Nanocomposites vs. Amorphous Solid Dispersions Prepared by Nanoextrusion Process

10.26226/morressier.57d6b2b8d462b8028d88d8de ◽

2016 ◽

Author(s):

Meng Li

Keyword(s):

Solid Dispersions ◽

Amorphous Solid ◽

Drug Dissolution ◽

Dissolution Enhancement ◽

Amorphous Solid Dispersions

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Improved Release of Celecoxib from High Drug Loading Amorphous Solid Dispersions Formulated with Polyacrylic Acid and Cellulose Derivatives

10.26226/morressier.57d6b2bbd462b8028d88d1d4 ◽

2016 ◽

Author(s):

Tian Xie

Keyword(s):

Polyacrylic Acid ◽

Drug Loading ◽

Solid Dispersions ◽

Amorphous Solid ◽

Cellulose Derivatives ◽

Amorphous Solid Dispersions ◽

High Drug ◽

High Drug Loading

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Development of novel darunavir amorphous solid dispersions with mesoporous carriers

European Journal of Pharmaceutical Sciences ◽

10.1016/j.ejps.2021.105700 ◽

2021 ◽

Vol 159 ◽

pp. 105700

Author(s):

Sergey A. Zolotov ◽

Natalia B. Demina ◽

Anna S. Zolotova ◽

Natalia V. Shevlyagina ◽

Grigorii A. Buzanov ◽

...

Keyword(s):

Solid Dispersions ◽

Amorphous Solid ◽

Amorphous Solid Dispersions

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