amorphous solid dispersions Latest Research Papers

Impact of Surfactants on the Performance of Clopidogrel-Copovidone Amorphous Solid Dispersions: Increased Drug Loading and Stabilization of Nanodroplets

Pharmaceutical Research ◽

10.1007/s11095-021-03159-w ◽

2022 ◽

Author(s):

Clara E. Correa Soto ◽

Yi Gao ◽

Anura S. Indulkar ◽

Keisuke Ueda ◽

Geoff G. Z. Zhang ◽

...

Keyword(s):

Drug Loading ◽

Solid Dispersions ◽

Amorphous Solid ◽

Amorphous Solid Dispersions

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Hot-melt extrudability of amorphous solid dispersions of flubendazole-copovidone: An exploratory study of the effect of drug loading and the balance of adjuvants on extrudability and dissolution

International Journal of Pharmaceutics ◽

10.1016/j.ijpharm.2022.121456 ◽

2022 ◽

pp. 121456

Author(s):

João M. C. de Assis ◽

Eduardo J. Barbosa ◽

Vinícius D.N. Bezzon ◽

Felipe R. Lourenço ◽

Flavio M.S. Carvalho ◽

...

Keyword(s):

Exploratory Study ◽

Drug Loading ◽

Solid Dispersions ◽

Amorphous Solid ◽

Amorphous Solid Dispersions ◽

Hot Melt

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Hot-melt extruded hydroxypropyl methylcellulose acetate succinate based amorphous solid dispersions: Impact of polymeric combinations on supersaturation kinetics and dissolution performance

International Journal of Pharmaceutics ◽

10.1016/j.ijpharm.2022.121471 ◽

2022 ◽

pp. 121471

Author(s):

Arun Butreddy ◽

Sandeep Sarabu ◽

Mashan Almutairi ◽

Srinivas Ajjarapu ◽

Praveen Kolimi ◽

...

Keyword(s):

Solid Dispersions ◽

Hydroxypropyl Methylcellulose ◽

Amorphous Solid ◽

Amorphous Solid Dispersions ◽

Hot Melt

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Industry White Paper: Contemporary Opportunities and Challenges in Characterizing Crystallinity in Amorphous Solid Dispersions

Journal of Pharmaceutical Sciences ◽

10.1016/j.xphs.2022.01.007 ◽

2022 ◽

Author(s):

Tyson Chasse ◽

Stephen L Conway ◽

Gerald D Danzer ◽

Lili Feng ◽

Anthony M Leone ◽

...

Keyword(s):

Solid Dispersions ◽

Amorphous Solid ◽

White Paper ◽

Amorphous Solid Dispersions

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Insights into the Release Mechanisms of ITZ:HPMCAS Amorphous Solid Dispersions: The Role of Drug-Rich Colloids

Molecular Pharmaceutics ◽

10.1021/acs.molpharmaceut.1c00578 ◽

2021 ◽

Author(s):

Patrícia D. Nunes ◽

João F. Pinto ◽

João Henriques ◽

A. Mafalda Paiva

Keyword(s):

Solid Dispersions ◽

Amorphous Solid ◽

Amorphous Solid Dispersions ◽

Release Mechanisms

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Impact of Polymer Type on Thermal Degradation of Amorphous Solid Dispersions Containing Ritonavir

Molecular Pharmaceutics ◽

10.1021/acs.molpharmaceut.1c00823 ◽

2021 ◽

Author(s):

Benedito Roberto de Alvarenga ◽

Dana E. Moseson ◽

Renato Lajarim Carneiro ◽

Lynne S. Taylor

Keyword(s):

Thermal Degradation ◽

Solid Dispersions ◽

Amorphous Solid ◽

Amorphous Solid Dispersions ◽

Polymer Type

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pH-Dependent supersaturation from amorphous solid dispersions of weakly basic drugs

Pharmaceutical Research ◽

10.1007/s11095-021-03147-0 ◽

2021 ◽

Author(s):

Bo Wang ◽

Matthew J. Nethercott ◽

Akshay Narula ◽

Michael Hanrahan ◽

Shanming Kuang ◽

...

Keyword(s):

Solid Dispersions ◽

Amorphous Solid ◽

Basic Drugs ◽

Amorphous Solid Dispersions ◽

Ph Dependent

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Amorphous Solid Dispersions: Utilization and Challenges in Preclinical Drug Development within AstraZeneca

International Journal of Pharmaceutics ◽

10.1016/j.ijpharm.2021.121387 ◽

2021 ◽

pp. 121387

Author(s):

Akosua B. Anane-Adjei ◽

Esther Jacobs ◽

Samuel C. Nash ◽

Sean Askin ◽

Ramesh Soundararajan ◽

...

Keyword(s):

Drug Development ◽

Solid Dispersions ◽

Amorphous Solid ◽

Amorphous Solid Dispersions ◽

Preclinical Drug Development

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On the usefulness of four in vitro methodologies in screening for product related differences in tacrolimus exposure after oral administration of amorphous solid dispersions with modified release characteristics in the fasted state

Journal of Drug Delivery Science and Technology ◽

10.1016/j.jddst.2021.102990 ◽

2021 ◽

pp. 102990

Author(s):

Georgia Tsakiridou ◽

Patrick J. O'Dwyer ◽

Antonios Margaritis ◽

Karl J. Box ◽

Maria Vertzoni ◽

...

Keyword(s):

Oral Administration ◽

Solid Dispersions ◽

Amorphous Solid ◽

Modified Release ◽

Amorphous Solid Dispersions ◽

Fasted State

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Increasing Drug Loading of Weakly Acidic Telmisartan in Amorphous Solid Dispersions through pH Modification during Hot-Melt Extrusion

Molecular Pharmaceutics ◽

10.1021/acs.molpharmaceut.1c00805 ◽

2021 ◽

Author(s):

Stephen A. Thompson ◽

Daniel A. Davis ◽

Chaeho Moon ◽

Robert O. Williams

Keyword(s):

Drug Loading ◽

Solid Dispersions ◽

Amorphous Solid ◽

Hot Melt Extrusion ◽

Melt Extrusion ◽

Amorphous Solid Dispersions ◽

Hot Melt

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amorphous solid dispersions
Recently Published Documents

TOTAL DOCUMENTS

H-INDEX

Impact of Surfactants on the Performance of Clopidogrel-Copovidone Amorphous Solid Dispersions: Increased Drug Loading and Stabilization of Nanodroplets

Hot-melt extrudability of amorphous solid dispersions of flubendazole-copovidone: An exploratory study of the effect of drug loading and the balance of adjuvants on extrudability and dissolution

Hot-melt extruded hydroxypropyl methylcellulose acetate succinate based amorphous solid dispersions: Impact of polymeric combinations on supersaturation kinetics and dissolution performance

Industry White Paper: Contemporary Opportunities and Challenges in Characterizing Crystallinity in Amorphous Solid Dispersions

Insights into the Release Mechanisms of ITZ:HPMCAS Amorphous Solid Dispersions: The Role of Drug-Rich Colloids

Impact of Polymer Type on Thermal Degradation of Amorphous Solid Dispersions Containing Ritonavir

pH-Dependent supersaturation from amorphous solid dispersions of weakly basic drugs

Amorphous Solid Dispersions: Utilization and Challenges in Preclinical Drug Development within AstraZeneca

On the usefulness of four in vitro methodologies in screening for product related differences in tacrolimus exposure after oral administration of amorphous solid dispersions with modified release characteristics in the fasted state

Increasing Drug Loading of Weakly Acidic Telmisartan in Amorphous Solid Dispersions through pH Modification during Hot-Melt Extrusion

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amorphous solid dispersionsRecently Published Documents

TOTAL DOCUMENTS

H-INDEX

Impact of Surfactants on the Performance of Clopidogrel-Copovidone Amorphous Solid Dispersions: Increased Drug Loading and Stabilization of Nanodroplets

Hot-melt extrudability of amorphous solid dispersions of flubendazole-copovidone: An exploratory study of the effect of drug loading and the balance of adjuvants on extrudability and dissolution

Hot-melt extruded hydroxypropyl methylcellulose acetate succinate based amorphous solid dispersions: Impact of polymeric combinations on supersaturation kinetics and dissolution performance

Industry White Paper: Contemporary Opportunities and Challenges in Characterizing Crystallinity in Amorphous Solid Dispersions

Insights into the Release Mechanisms of ITZ:HPMCAS Amorphous Solid Dispersions: The Role of Drug-Rich Colloids

Impact of Polymer Type on Thermal Degradation of Amorphous Solid Dispersions Containing Ritonavir

pH-Dependent supersaturation from amorphous solid dispersions of weakly basic drugs

Amorphous Solid Dispersions: Utilization and Challenges in Preclinical Drug Development within AstraZeneca

On the usefulness of four in vitro methodologies in screening for product related differences in tacrolimus exposure after oral administration of amorphous solid dispersions with modified release characteristics in the fasted state

Increasing Drug Loading of Weakly Acidic Telmisartan in Amorphous Solid Dispersions through pH Modification during Hot-Melt Extrusion

amorphous solid dispersions
Recently Published Documents