Cysteine 148 in the Lactose Permease of Escherichia coli Is a Component of a Substrate Binding Site. 1. Site-Directed Mutagenesis Studies

Directed Mutagenesis ◽

Lactose Permease ◽

Evidence for an arginine residue at the substrate binding site of Escherichia coli adenylosuccinate synthetase as studied by chemical modification and site-directed mutagenesis

Journal of Biological Chemistry ◽

10.1016/s0021-9258(18)98886-1 ◽

1991 ◽

Vol 266 (19) ◽

pp. 12228-12233

Author(s):

Q. Dong ◽

F. Liu ◽

A.M. Myers ◽

H.J. Fromm

Keyword(s):

Escherichia Coli ◽

Chemical Modification ◽

Binding Site ◽

Substrate Binding ◽

Arginine Residue ◽

Directed Mutagenesis ◽

Substrate Binding Site ◽

Adenylosuccinate Synthetase

Identification of an amino acid residue involved in the substrate-binding site of rat liver uricase by site-directed mutagenesis

Biochemical and Biophysical Research Communications ◽

10.1016/s0006-291x(05)81464-0 ◽

1992 ◽

Vol 187 (1) ◽

pp. 101-107 ◽

Cited By ~ 4

Author(s):

Masaki Ito ◽

Seiya Kato ◽

Masamichi Nakamura ◽

Go Mitiko ◽

Yasuyuki Takagi

Keyword(s):

Amino Acid ◽

Binding Site ◽

Rat Liver ◽

Amino Acid Residue ◽

Substrate Binding ◽

Directed Mutagenesis ◽

Conformational flexibility at the substrate binding site in the lactose permease of Escherichia coli

Proceedings of the National Academy of Sciences ◽

10.1073/pnas.96.20.11178 ◽

1999 ◽

Vol 96 (20) ◽

pp. 11178-11182 ◽

Cited By ~ 16

Author(s):

A. B. Weinglass ◽

H. R. Kaback

Keyword(s):

Escherichia Coli ◽

Binding Site ◽

Substrate Binding ◽

Conformational Flexibility ◽

Lactose Permease ◽

Identification of putative residues involved in the accessibility of the substrate-binding site of lipoxygenase by site-directed mutagenesis studies

Archives of Biochemistry and Biophysics ◽

10.1016/j.abb.2011.02.008 ◽

2011 ◽

Vol 509 (1) ◽

pp. 82-89 ◽

Cited By ~ 9

Author(s):

Cynthia Palmieri-Thiers ◽

Jean-Christophe Alberti ◽

Stéphane Canaan ◽

Virginie Brunini ◽

Claude Gambotti ◽

...

Keyword(s):

Binding Site ◽

Substrate Binding ◽

Directed Mutagenesis ◽

Probing the 2,4-Dichlorophenoxyacetate/α-Ketoglutarate Dioxygenase Substrate-Binding Site by Site-Directed Mutagenesis and Mechanism-Based Inactivation†

Biochemistry ◽

10.1021/bi026057a ◽

2002 ◽

Vol 41 (31) ◽

pp. 9787-9794 ◽

Cited By ~ 15

Author(s):

Julie C. Dunning Hotopp ◽

Robert P. Hausinger

Keyword(s):

Binding Site ◽

Substrate Binding ◽

Directed Mutagenesis ◽

Substrate Binding Site ◽

Ketoglutarate Dioxygenase

Site-Directed Mutagenesis of the Substrate Binding Site of Porcine Fructose-1,6-bisphosphatase

Archives of Biochemistry and Biophysics ◽

10.1006/abbi.1995.1273 ◽

1995 ◽

Vol 319 (1) ◽

pp. 123-127 ◽

Cited By ~ 7

Author(s):

L.F. Shyur ◽

R.L. Zhang ◽

H.J. Fromm

Keyword(s):

Binding Site ◽

Substrate Binding ◽

Directed Mutagenesis ◽

Substrate Binding Site ◽

Fructose 1,6 Bisphosphatase

The substrate-binding site in the lactose permease of Escherichia coli

Proceedings of the National Academy of Sciences ◽

10.1073/pnas.95.17.9802 ◽

1998 ◽

Vol 95 (17) ◽

pp. 9802-9807 ◽

Cited By ~ 51

Author(s):

P. Venkatesan ◽

H. R. Kaback

Keyword(s):

Escherichia Coli ◽

Binding Site ◽

Substrate Binding ◽

Lactose Permease ◽

Site-directed mutagenesis of residues at the substrate binding-site of myeloperoxidase

Journal of Inorganic Biochemistry ◽

10.1016/s0162-0134(97)89965-5 ◽

1997 ◽

Vol 67 (1-4) ◽

pp. 85

Author(s):

Ingeborg M. Kooter ◽

Nicole Moguilevsky ◽

Alex Bollen ◽

Marianna Sijtsema ◽

Kees Otto ◽

...

Keyword(s):

Binding Site ◽

Substrate Binding ◽

Directed Mutagenesis ◽

Analysis of the substrate-binding site of human carbonyl reductases CBR1 and CBR3 by site-directed mutagenesis

Chemico-Biological Interactions ◽

10.1016/j.cbi.2008.11.004 ◽

2009 ◽

Vol 178 (1-3) ◽

pp. 234-241 ◽

Cited By ~ 23

Author(s):

Yasser El-Hawari ◽

Angelo D. Favia ◽

Ewa S. Pilka ◽

Michael Kisiela ◽

Udo Oppermann ◽

...

Keyword(s):

Binding Site ◽

Substrate Binding ◽

Directed Mutagenesis ◽

Cysteine 148 in the Lactose Permease of Escherichia coli Is a Component of a Substrate Binding Site. 2. Site-Directed Fluorescence Studies

Biochemistry ◽

10.1021/bi00206a020 ◽

1994 ◽

Vol 33 (40) ◽

pp. 12166-12171 ◽

Cited By ~ 48

Author(s):

Jianhua Wu ◽

H. Ronald Kaback

Keyword(s):

Escherichia Coli ◽

Binding Site ◽

Substrate Binding ◽

Lactose Permease ◽

Substrate Binding Site ◽

Fluorescence Studies