Role of the S128, H186, and N187 Triad in Substrate Binding and Decarboxylation in the Sheep Liver 6-Phosphogluconate Dehydrogenase Reaction†

Biochemistry ◽  
2006 ◽  
Vol 45 (42) ◽  
pp. 12680-12686 ◽  
Author(s):  
Lei Li ◽  
Lei Zhang ◽  
Paul F. Cook
Keyword(s):  
Substrate Binding ◽  
Phosphogluconate Dehydrogenase ◽  
Sheep Liver ◽  
Dehydrogenase Reaction

scholarly journals The nature of carbon dioxide substrate and equilibrium constant of the 6-phosphogluconate dehydrogenase reaction

1969 ◽  
Vol 115 (4) ◽  
pp. 633-638 ◽  
Author(s):  
R. H. Villet ◽  
K. Dalziel
Keyword(s):  
Carbon Dioxide ◽  
Free Energy ◽  
Equilibrium Constant ◽  
Heat Of Reaction ◽  
Phosphogluconate Dehydrogenase ◽  
Sheep Liver ◽  
Dehydrogenase Reaction ◽  
Reductive Carboxylation ◽  
Primary Substrate

1. It was shown that dissolved CO2 and not HCO3− or H2CO3 is the primary substrate for reductive carboxylation with 6-phosphogluconate dehydrogenase from sheep liver. 2. The equilibrium constant of the reaction was measured in solutions of various ionic strengths and at several temperatures, and the free energy and heat of reaction were determined.

Role of Methionine-13 in the Catalytic Mechanism of 6-Phosphogluconate Dehydrogenase from Sheep Liver†

Biochemistry ◽  
2005 ◽  
Vol 44 (7) ◽  
pp. 2432-2440 ◽  
Author(s):  
Carlo Cervellati ◽  
Franco Dallocchio ◽  
Carlo M. Bergamini ◽  
Paul F. Cook
Keyword(s):  
Catalytic Mechanism ◽  
Phosphogluconate Dehydrogenase ◽  
Sheep Liver

The role of Glu196 in the environment around the substrate binding site of leucine aminopeptidase fromStreptomyces griseus

FEBS Letters ◽  
2006 ◽  
Vol 580 (3) ◽  
pp. 912-917 ◽  
Author(s):  
Jiro Arima ◽  
Yoshiko Uesugi ◽  
Misugi Uraji ◽  
Masaki Iwabuchi ◽  
Tadashi Hatanaka
Keyword(s):  
Binding Site ◽  
Leucine Aminopeptidase ◽  
Substrate Binding ◽  
Substrate Binding Site

Role of Cytochrome P450 in Tulip Bulb Probed by Substrate-Binding Studies

1992 ◽  
Vol 36 (1) ◽  
pp. 27-30 ◽  
Author(s):  
Steven L. Kelly ◽  
Aysegul Topal ◽  
Ian Barnett ◽  
Diane E. Kelly ◽  
George A. F. Hendry
Keyword(s):  
Cytochrome P450 ◽  
Substrate Binding ◽  
Binding Studies ◽  
Tulip Bulb

Cloning, Expression, Purification, and Characterization of the 6-Phosphogluconate Dehydrogenase from Sheep Liver

1998 ◽  
Vol 13 (2) ◽  
pp. 251-258 ◽  
Author(s):  
Lilian Chooback ◽  
Nancy E. Price ◽  
William E. Karsten ◽  
John Nelson ◽  
Paula Sundstrom ◽  
...  
Keyword(s):  
Purification And Characterization ◽  
Phosphogluconate Dehydrogenase ◽  
Sheep Liver
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