Substrate Orientation and Specificity in Xanthine Oxidase: Crystal Structures of the Enzyme in Complex with Indole-3-acetaldehyde and Guanine

Biochemistry ◽  
2014 ◽  
Vol 53 (3) ◽  
pp. 533-541 ◽  
Author(s):  
Hongnan Cao ◽  
James Hall ◽  
Russ Hille
Keyword(s):  
Xanthine Oxidase ◽  
Crystal Structures ◽  
Substrate Orientation

scholarly journals Xanthine oxidase–product complexes probe the importance of substrate/product orientation along the reaction coordinate

2017 ◽  
Vol 46 (39) ◽  
pp. 13242-13250 ◽  
Author(s):  
Jing Yang ◽  
Chao Dong ◽  
Martin L. Kirk
Keyword(s):  
Raman Spectroscopy ◽  
Hydrogen Bonding ◽  
Xanthine Oxidase ◽  
Resonance Raman Spectroscopy ◽  
Resonance Raman ◽  
Reaction Coordinate ◽  
Substrate Orientation ◽  
Hydrogen Bonding Interactions

Resonance Raman spectroscopy has been used to probe substrate orientation and hydrogen bonding interactions in a xanthine oxidase catalytic intermediate.

scholarly journals Substrate Orientation and Catalytic Specificity in the Action of Xanthine Oxidase

2010 ◽  
Vol 285 (36) ◽  
pp. 28044-28053 ◽  
Author(s):  
Hongnan Cao ◽  
James M. Pauff ◽  
Russ Hille
Keyword(s):  
Xanthine Oxidase ◽  
Substrate Orientation

scholarly journals Xanthine Oxidase Inhibitory Activities and Crystal Structures of Methoxyflavones from Kaempferia parviflora Rhizome

2011 ◽  
Vol 34 (7) ◽  
pp. 1143-1146 ◽  
Author(s):  
Kikuyo Nakao ◽  
Kazuya Murata ◽  
Takahiro Deguchi ◽  
Kimihisa Itoh ◽  
Takanori Fujita ◽  
...  
Keyword(s):  
Xanthine Oxidase ◽  
Crystal Structures ◽  
Kaempferia Parviflora ◽  
Inhibitory Activities

Synthesis, crystal structures, fluorescence and xanthine oxidase inhibitory activity of pyrazole-based 1,3,4-oxadiazole derivatives

2015 ◽  
Vol 1100 ◽  
pp. 421-428 ◽  
Author(s):  
De-Qiang Qi ◽  
Chuan-Ming Yu ◽  
Jin-Zong You ◽  
Guang-Hui Yang ◽  
Xue-Jie Wang ◽  
...  
Keyword(s):  
Xanthine Oxidase ◽  
Crystal Structures ◽  
Inhibitory Activity ◽  
Oxadiazole Derivatives

scholarly journals Substrate Orientation in Xanthine Oxidase

2007 ◽  
Vol 283 (8) ◽  
pp. 4818-4824 ◽  
Author(s):  
James M. Pauff ◽  
Jinjin Zhang ◽  
Charles E. Bell ◽  
Russ Hille
Keyword(s):  
Xanthine Oxidase ◽  
Substrate Orientation
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