Inhibition of Nicotinic Acetylcholine Receptor by Philanthotoxin-343:  Kinetic Investigations in the Microsecond Time Region Using a Laser-Pulse Photolysis Technique†

Vasanthi Jayaraman; Peter N. R. Usherwood; George P. Hess

doi:10.1021/bi991219x

Inhibition of Nicotinic Acetylcholine Receptor by Philanthotoxin-343: Kinetic Investigations in the Microsecond Time Region Using a Laser-Pulse Photolysis Technique†

Biochemistry ◽

10.1021/bi991219x ◽

1999 ◽

Vol 38 (35) ◽

pp. 11406-11414 ◽

Cited By ~ 21

Author(s):

Vasanthi Jayaraman ◽

Peter N. R. Usherwood ◽

George P. Hess

Keyword(s):

Laser Pulse ◽

Acetylcholine Receptor ◽

Nicotinic Acetylcholine Receptor ◽

Pulse Photolysis ◽

Nicotinic Acetylcholine ◽

Laser Pulse Photolysis ◽

Time Region ◽

Kinetic Investigations

On the Mechanism of Inhibition of the Nicotinic Acetylcholine Receptor by the Anticonvulsant MK-801 Investigated by Laser-Pulse Photolysis in the Microsecond-to-Millisecond Time Region†

Biochemistry ◽

10.1021/bi9827767 ◽

1999 ◽

Vol 38 (24) ◽

pp. 7837-7846 ◽

Cited By ~ 19

Author(s):

Christof Grewer ◽

George P. Hess

Keyword(s):

Laser Pulse ◽

Acetylcholine Receptor ◽

Nicotinic Acetylcholine Receptor ◽

Pulse Photolysis ◽

Nicotinic Acetylcholine ◽

Mk 801 ◽

Mechanism Of Inhibition ◽

Laser Pulse Photolysis ◽

Time Region

How Fast Does the γ-Aminobutyric Acid Receptor Channel Open? Kinetic Investigations in the Microsecond Time Region Using a Laser-Pulse Photolysis Technique†

Biochemistry ◽

10.1021/bi990454c ◽

1999 ◽

Vol 38 (35) ◽

pp. 11372-11378 ◽

Cited By ~ 16

Author(s):

Vasanthi Jayaraman ◽

Shalita Thiran ◽

George P. Hess

Keyword(s):

Laser Pulse ◽

Aminobutyric Acid ◽

Pulse Photolysis ◽

Acid Receptor ◽

Laser Pulse Photolysis ◽

Time Region ◽

Kinetic Investigations ◽

Receptor Channel

An acetylcholine receptor regulatory site in BC3H1 cells: Characterized by laser-pulse photolysis in the microsecond-to-millisecond time region

Biochemistry ◽

10.1021/bi00066a001 ◽

1993 ◽

Vol 32 (15) ◽

pp. 3831-3835 ◽

Cited By ~ 31

Author(s):

Li Niu ◽

George P. Hess

Keyword(s):

Laser Pulse ◽

Acetylcholine Receptor ◽

Regulatory Site ◽

Pulse Photolysis ◽

Laser Pulse Photolysis ◽

Time Region

How fast does an acetylcholine receptor channel open? Laser-pulse photolysis of an inactive precursor of carbamoylcholine in the microsecond time region with BC3H1 cells

Biochemistry ◽

10.1021/bi00139a012 ◽

1992 ◽

Vol 31 (24) ◽

pp. 5507-5514 ◽

Cited By ~ 35

Author(s):

Norio Matsubara ◽

Andrew P. Billington ◽

George P. Hess

Keyword(s):

Laser Pulse ◽

Acetylcholine Receptor ◽

Pulse Photolysis ◽

Laser Pulse Photolysis ◽

Time Region ◽

Acetylcholine Receptor Channel ◽

Receptor Channel

Cocaine: mechanism of inhibition of a muscle acetylcholine receptor studied by a laser-pulse photolysis technique.

Proceedings of the National Academy of Sciences ◽

10.1073/pnas.92.26.12008 ◽

1995 ◽

Vol 92 (26) ◽

pp. 12008-12012 ◽

Cited By ~ 21

Author(s):

L. Niu ◽

L. G. Abood ◽

G. P. Hess

Keyword(s):

Laser Pulse ◽

Acetylcholine Receptor ◽

Pulse Photolysis ◽

Mechanism Of Inhibition ◽

Laser Pulse Photolysis

Channel-Opening Mechanism of a Kainate-Activated Glutamate Receptor: Kinetic Investigations Using a Laser-Pulse Photolysis Technique†

Biochemistry ◽

10.1021/bi9813328 ◽

1998 ◽

Vol 37 (47) ◽

pp. 16735-16740 ◽

Cited By ~ 9

Author(s):

Vasanthi Jayaraman

Keyword(s):

Laser Pulse ◽

Glutamate Receptor ◽

Pulse Photolysis ◽

Channel Opening ◽

Laser Pulse Photolysis ◽

Kinetic Investigations ◽

Receptor Kinetic

PROTEIN CONFORMATIONAL CHANGES IN THE μs TIME REGION INVESTIGATED WITH A LASER PULSE PHOTOLYSIS TECHNIQUE11We gratefully acknowledge financial support by grants (GM04942 and RR04804) awarded to G.P.H. by the National Institutes of Health.

Techniques in Protein Chemistry III ◽

10.1016/b978-0-12-058756-8.50047-x ◽

1992 ◽

pp. 417-427

Author(s):

Andrew P. Billington ◽

Norio Matsubara ◽

Watt W. Webb ◽

George P. Hess

Keyword(s):

Laser Pulse ◽

Conformational Changes ◽

Financial Support ◽

National Institutes Of Health ◽

Pulse Photolysis ◽

Protein Conformational Changes ◽

Laser Pulse Photolysis ◽

Time Region

Efficacy of Varenicline, an α4β2 Nicotinic Acetylcholine Receptor Partial Agonist, vs Placebo or Sustained-Release Bupropion for Smoking Cessation: A Randomized Controlled Trial

Yearbook of Pulmonary Disease ◽

10.1016/s8756-3452(08)70598-x ◽

2008 ◽

Vol 2008 ◽

pp. 109-110

Author(s):

L.T. Tanoue

Keyword(s):

Randomized Controlled Trial ◽

Smoking Cessation ◽

Sustained Release ◽

Acetylcholine Receptor ◽

Nicotinic Acetylcholine Receptor ◽

Partial Agonist ◽

Controlled Trial ◽

Nicotinic Acetylcholine ◽

Randomized Controlled

Varenicline, an α4β2 Nicotinic Acetylcholine Receptor Partial Agonist, vs Sustained-Release Bupropion and Placebo for Smoking Cessation: A Randomized Controlled Trial

Yearbook of Medicine ◽

10.1016/s0084-3873(08)70096-8 ◽

2007 ◽

Vol 2007 ◽

pp. 143-145

Author(s):

N.H. Hanna

Keyword(s):

Randomized Controlled Trial ◽

Smoking Cessation ◽

Sustained Release ◽

Acetylcholine Receptor ◽

Nicotinic Acetylcholine Receptor ◽

Partial Agonist ◽

Controlled Trial ◽

Nicotinic Acetylcholine ◽

Randomized Controlled

Faculty Opinions recommendation of Decreased signs of nicotine withdrawal in mice null for the beta4 nicotinic acetylcholine receptor subunit.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.1022312.254647 ◽

2004 ◽

Author(s):

Marina Picciotto

Keyword(s):

Acetylcholine Receptor ◽

Nicotinic Acetylcholine Receptor ◽

Nicotine Withdrawal ◽

Receptor Subunit ◽

Nicotinic Acetylcholine