Enantioselective synthesis of the carbocyclic nucleosides (-)-aristeromycin and (-)-neplanocin A by a chemicoenzymatic approach

1983 ◽  
Vol 105 (12) ◽  
pp. 4049-4055 ◽  
Author(s):  
Masafumi Arita ◽  
Kunitomo Adachi ◽  
Yukishige Ito ◽  
Hiroaki Sawai ◽  
Masaji Ohno
Keyword(s):  
Enantioselective Synthesis ◽  
Carbocyclic Nucleosides ◽  
Neplanocin A

ChemInform Abstract: Expeditious Enantioselective Synthesis of Carbocyclic Nucleosides with Antileishmanial Activity.

ChemInform ◽  
2010 ◽  
Vol 25 (2) ◽  
pp. no-no
Author(s):  
A. D. DA SILVA ◽  
E. S. COIMBRA ◽  
J.-L. FOURREY ◽  
A. S. MACHADO ◽  
M. ROBERT-GERO
Keyword(s):  
Enantioselective Synthesis ◽  
Antileishmanial Activity ◽  
Carbocyclic Nucleosides

ChemInform Abstract: Synthesis of Carbocyclic Nucleosides, (-)-Neplanocin A and Its Analogues.

ChemInform ◽  
2010 ◽  
Vol 25 (51) ◽  
pp. no-no
Author(s):  
J. NOKAMI ◽  
H. MATSUURA ◽  
H. TAKAHASHI ◽  
M. YAMASHITA
Keyword(s):  
Carbocyclic Nucleosides ◽  
Neplanocin A

Synthesis of Carbocyclic Nucleosides (+)-Neplanocin A, (+)-Aristeromycin and 4'-epi-(+)-Aristeromycin from D-Fructose

2019 ◽  
Vol 16 (9) ◽  
pp. 750-758
Author(s):  
Perali R. Sridhar ◽  
Vennam D.K. Reddy ◽  
Mandava Suresh ◽  
Nadiveedhi M. Reddy ◽  
K. Shiva Kumar
Keyword(s):  
Total Synthesis ◽  
Allylic Alcohol ◽  
Starting Material ◽  
Carbocyclic Nucleosides ◽  
Ring Closing Metathesis ◽  
Neplanocin A ◽  
Oxidative Rearrangement ◽  
Key Steps

D-Fructose is used as the chiral pool starting material for the stereoselective total synthesis of (+)-neplanocin A. Zinc mediated fragmentation, ring-closing metathesis and oxidative rearrangement of cyclic tertiary allylic alcohol are used as the key steps in achieving the synthesis of key carbocylic intermediate. Further, stereoselective total synthesis of 4'-epi-(+)-aristeromycin and the conversion of (+)-neplanocin A to a mixture of (+)-aristeromycin and 4'-epi-(+)-aristeromycin are described.

ChemInform Abstract: Advances in the Enantioselective Synthesis of Carbocyclic Nucleosides

ChemInform ◽  
2013 ◽  
Vol 44 (36) ◽  
pp. no-no
Author(s):  
Omar Boutureira ◽  
M. Isabel Matheu ◽  
Yolanda Diaz ◽  
Sergio Castillon
Keyword(s):  
Enantioselective Synthesis ◽  
Carbocyclic Nucleosides

Enantioselective synthesis of new analogs of neplanocin A and their biological activity

1987 ◽  
Vol 171 (1) ◽  
pp. 233-258 ◽  
Author(s):  
Masafumi Arita ◽  
Takeki Okumoto ◽  
Tadamasa Saito ◽  
Yukio Hoshino ◽  
Kiyofumi Fukukawa ◽  
...  
Keyword(s):  
Biological Activity ◽  
Enantioselective Synthesis ◽  
Neplanocin A
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