Enantioselective Synthesis of Alkyne-Substituted Quaternary Carbon Stereogenic Centers through NHC−Cu-Catalyzed Allylic Substitution Reactions with (i-Bu)2(Alkynyl)aluminum Reagents

Jennifer A. Dabrowski; Fang Gao; Amir H. Hoveyda

doi:10.1021/ja2010829

Enantioselective Synthesis of Alkyne-Substituted Quaternary Carbon Stereogenic Centers through NHC−Cu-Catalyzed Allylic Substitution Reactions with (i-Bu)2(Alkynyl)aluminum Reagents

Journal of the American Chemical Society ◽

10.1021/ja2010829 ◽

2011 ◽

Vol 133 (13) ◽

pp. 4778-4781 ◽

Cited By ~ 105

Author(s):

Jennifer A. Dabrowski ◽

Fang Gao ◽

Amir H. Hoveyda

Keyword(s):

Enantioselective Synthesis ◽

Allylic Substitution ◽

Quaternary Carbon ◽

Substitution Reactions ◽

Stereogenic Centers

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ChemInform Abstract: Enantioselective Synthesis of Alkyne-Substituted Quaternary Carbon Stereogenic Centers Through NHC-Cu-Catalyzed Allylic Substitution Reactions with (iBu)2(Alkynyl)aluminum Reagents.

ChemInform ◽

10.1002/chin.201134060 ◽

2011 ◽

Vol 42 (34) ◽

pp. no-no

Author(s):

Jennifer A. Dabrowski ◽

Fang Gao ◽

Amir H. Hoveyda

Keyword(s):

Enantioselective Synthesis ◽

Allylic Substitution ◽

Quaternary Carbon ◽

Substitution Reactions ◽

Stereogenic Centers

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Regio‐ and Enantioselective Synthesis of Sulfone‐Bearing Quaternary Carbon Stereocenters by Pd‐Catalyzed Allylic Substitution

Angewandte Chemie ◽

10.1002/ange.201910378 ◽

2019 ◽

Vol 132 (3) ◽

pp. 1356-1361 ◽

Cited By ~ 2

Author(s):

Ajmal Khan ◽

Heng Zhao ◽

Meina Zhang ◽

Shahid Khan ◽

Depeng Zhao

Keyword(s):

Enantioselective Synthesis ◽

Allylic Substitution ◽

Quaternary Carbon

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Enantioselective Synthesis of Quaternary Carbon Stereogenic Centers through Copper-Catalyzed Conjugate Additions of Aryl- and Alkylaluminum Reagents to Acyclic Trisubstituted Enones

Angewandte Chemie International Edition ◽

10.1002/anie.201304035 ◽

2013 ◽

Vol 52 (31) ◽

pp. 8156-8159 ◽

Cited By ~ 46

Author(s):

Jennifer A. Dabrowski ◽

Matthew T. Villaume ◽

Amir H. Hoveyda

Keyword(s):

Enantioselective Synthesis ◽

Quaternary Carbon ◽

Conjugate Additions ◽

Stereogenic Centers

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Regio‐ and Enantioselective Synthesis of Sulfone‐Bearing Quaternary Carbon Stereocenters by Pd‐Catalyzed Allylic Substitution

Angewandte Chemie International Edition ◽

10.1002/anie.201910378 ◽

2019 ◽

Vol 59 (3) ◽

pp. 1340-1345 ◽

Cited By ~ 15

Author(s):

Ajmal Khan ◽

Heng Zhao ◽

Meina Zhang ◽

Shahid Khan ◽

Depeng Zhao

Keyword(s):

Enantioselective Synthesis ◽

Allylic Substitution ◽

Quaternary Carbon

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Regio- and Stereoselectivity in the Reactions of Organometallic Reagents with an Electron-Deficient and an Electron-Rich Vinyloxirane: Applications for Sequential Bis-Allylic Substitution Reactions in the Generation of Vicinal Stereogenic Centers

The Journal of Organic Chemistry ◽

10.1021/jo300304n ◽

2012 ◽

Vol 77 (11) ◽

pp. 4949-4967 ◽

Cited By ~ 12

Author(s):

R. Karl Dieter ◽

Yaxin Huang ◽

Fenghai Guo

Keyword(s):

Allylic Substitution ◽

Substitution Reactions ◽

Organometallic Reagents ◽

Stereogenic Centers

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ChemInform Abstract: Rhodium-Catalyzed Allylic Substitution with an Acyl Anion Equivalent: Stereospecific Construction of Acyclic Quaternary Carbon Stereogenic Centers.

ChemInform ◽

10.1002/chin.201319067 ◽

2013 ◽

Vol 44 (19) ◽

pp. no-no

Author(s):

P. Andrew Evans ◽

Samuel Oliver ◽

Jungha Chae

Keyword(s):

Allylic Substitution ◽

Quaternary Carbon ◽

Stereogenic Centers ◽

Acyl Anion

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Enantioselective Rhodium-Catalyzed Allylic Substitution with a Nitrile Anion: Construction of Acyclic Quaternary Carbon Stereogenic Centers

Journal of the American Chemical Society ◽

10.1021/jacs.5b02810 ◽

2015 ◽

Vol 137 (19) ◽

pp. 6156-6159 ◽

Cited By ~ 60

Author(s):

Ben W. H. Turnbull ◽

P. Andrew Evans

Keyword(s):

Allylic Substitution ◽

Quaternary Carbon ◽

Stereogenic Centers

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Catalytic Asymmetric Alkylations of Ketoimines. Enantioselective Synthesis ofN-Substituted Quaternary Carbon Stereogenic Centers by Zr-Catalyzed Additions of Dialkylzinc Reagents to Aryl-, Alkyl-, and Trifluoroalkyl-Substituted Ketoimines

Journal of the American Chemical Society ◽

10.1021/ja8001343 ◽

2008 ◽

Vol 130 (16) ◽

pp. 5530-5541 ◽

Cited By ~ 151

Author(s):

Peng Fu ◽

Marc L. Snapper ◽

Amir H. Hoveyda

Keyword(s):

Enantioselective Synthesis ◽

Quaternary Carbon ◽

Stereogenic Centers ◽

Catalytic Asymmetric ◽

Asymmetric Alkylations

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Rhodium-Catalyzed Allylic Substitution with an Acyl Anion Equivalent: Stereospecific Construction of Acyclic Quaternary Carbon Stereogenic Centers

Journal of the American Chemical Society ◽

10.1021/ja306602g ◽

2012 ◽

Vol 134 (47) ◽

pp. 19314-19317 ◽

Cited By ~ 60

Author(s):

P. Andrew Evans ◽

Samuel Oliver ◽

Jungha Chae

Keyword(s):

Allylic Substitution ◽

Quaternary Carbon ◽

Stereogenic Centers ◽

Acyl Anion

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Enantioselective Synthesis of Boron-Substituted Quaternary Carbon Stereogenic Centers through NHC-Catalyzed Conjugate Additions of (Pinacolato)boron Units to Enones

Angewandte Chemie International Edition ◽

10.1002/anie.201309982 ◽

2014 ◽

Vol 53 (13) ◽

pp. 3387-3391 ◽

Cited By ~ 75

Author(s):

Suttipol Radomkit ◽

Amir H. Hoveyda

Keyword(s):

Enantioselective Synthesis ◽

Quaternary Carbon ◽

Conjugate Additions ◽

Stereogenic Centers

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