Catalytic asymmetric Povarov protocols have undergone an explosive growth, especially in the last ten years, since the first example was published in 1996. The use of chiral Lewis and Brønsted...
Correction for ‘Catalytic asymmetric hydrometallation of cyclobutenes with salicylaldehydes’ by F. Wieland Goetzke et al., Chem. Sci., 2022, DOI: 10.1039/d1sc06035j.
Chiral, substituted cyclobutanes are common motifs in bioactive compounds and intermediates in organic synthesis but few asymmetric routes for their synthesis are known.
Chiral amines are widely found in nature, many of which possess significant biological and synthetic values. The catalytic asymmetric syntheses of optically active amines have inspired enormous interests. Currently, the...
The catalytic asymmetric α-benzylation of aldehydes represents a highly valuable reaction for organic synthesis. For example, the generated α-heteroarylmethyl aldehydes, such as (R)-2-methyl-3-(pyridin-4-yl)propanal ((R)-MPP), are an important class of synthons...