The First Synthesis of Herbicidin B. Stereoselective Construction of the Tricyclic Undecose Moiety by a Conformational Restriction Strategy Using Steric Repulsion between Adjacent Bulky Silyl Protecting Groups on a Pyranose Ring†

Synthesis of 3,7-Anhydro-d-glycero-d-ido-octitol 1,5,6-Trisphosphate as an IP3Receptor Ligand Using a Radical Cyclization Reaction with a Vinylsilyl Tether as the Key Step. Conformational Restriction Strategy Using Steric Repulsion between Adjacent Bulky Protecting Groups on a Pyranose Ring

The Journal of Organic Chemistry ◽

10.1021/jo0002339 ◽

2000 ◽

Vol 65 (18) ◽

pp. 5547-5557 ◽

Cited By ~ 35

Author(s):

Satoshi Shuto ◽

Yumi Yahiro ◽

Satoshi Ichikawa ◽

Akira Matsuda

Keyword(s):

Radical Cyclization ◽

Cyclization Reaction ◽

Protecting Groups ◽

Steric Repulsion ◽

Pyranose Ring ◽

Synthesis of C-glycosides via radical cyclization reactions with a vinylsilyl tether. Control of the reaction course by a change in the conformation of the pyranose ring due to steric repulsion between adjacent bulky protecting groups

Tetrahedron Letters ◽

10.1016/s0040-4039(99)01026-6 ◽

1999 ◽

Vol 40 (30) ◽

pp. 5527-5531 ◽

Cited By ~ 24

Author(s):

Yumi Yahiro ◽

Satoshi Ichikawa ◽

Satoshi Shuto ◽

Akira Matsuda

Keyword(s):

Radical Cyclization ◽

Protecting Groups ◽

Steric Repulsion ◽

Pyranose Ring ◽

Cyclization Reactions

ChemInform Abstract: Nucleosides and Nucleotides. Part 190. The First Synthesis of Herbicidin B. Stereoselective Construction of the Tricyclic Undecose Moiety by a Conformational Restriction Strategy Using Steric Repulsion Between Adjacent Bulky Silyl Pro

ChemInform ◽

10.1002/chin.200007220 ◽

2010 ◽

Vol 31 (7) ◽

pp. no-no

Author(s):

Satoshi Ichikawa ◽

Satoshi Shuto ◽

Akira Matsuda

Keyword(s):

Steric Repulsion ◽

ChemInform Abstract: Synthesis of C-Glycosides via Radical Cyclization Reactions with a Vinylsilyl Tether. Control of the Reaction Course by a Change in the Conformation of the Pyranose Ring due to Steric Repulsion Between Adjacent Bulky Protecting Groups

ChemInform ◽

10.1002/chin.199944225 ◽

2010 ◽

Vol 30 (44) ◽

pp. no-no

Author(s):

Yumi Yahiro ◽

Satoshi Ichikawa ◽

Satoshi Shuto ◽

Akira Matsuda

Keyword(s):

Radical Cyclization ◽

Protecting Groups ◽

Steric Repulsion ◽

Pyranose Ring ◽

Cyclization Reactions

ChemInform Abstract: Synthesis of 3,7-Anhydro-D-glycero-D-ido-octitol 1,5,6-Trisphosphate as an IP3 Receptor Ligand Using a Radical Cyclization Reaction with a Vinylsilyl Tether as the Key Step. Conformational Restriction Strategy Using Steric Repulsion B

ChemInform ◽

10.1002/chin.200051191 ◽

2000 ◽

Vol 31 (51) ◽

pp. no-no

Author(s):

Satoshi Shuto ◽

Yumi Yahiro ◽

Satoshi Ichikawa ◽

Akira Matsuda

Keyword(s):

Radical Cyclization ◽

Cyclization Reaction ◽

Steric Repulsion ◽

Ip3 Receptor ◽

Receptor Ligand ◽

Generation of tricyclic imidazo[1,2- a ]pyrazines as novel PI3K inhibitors by application of a conformational restriction strategy

Bioorganic & Medicinal Chemistry Letters ◽

10.1016/j.bmcl.2017.03.090 ◽

2017 ◽

Vol 27 (11) ◽

pp. 2536-2543 ◽

Cited By ~ 8

Author(s):

Sonia Martínez González ◽

Sonsoles Rodríguez-Arístegui ◽

Ana Isabel Hernández ◽

Carmen Varela ◽

Esther González Cantalapiedra ◽

...

Keyword(s):

Pi3k Inhibitors ◽

An Efficient Synthesis of β-C-Glycosides Based on the Conformational Restriction Strategy: Lewis Acid Promoted Silane Reduction of the Anomeric Position with Complete Stereoselectivity

Organic Letters ◽

10.1021/ol048525+ ◽

2004 ◽

Vol 6 (21) ◽

pp. 3751-3754 ◽

Cited By ~ 40

Author(s):

Masaru Terauchi ◽

Hiroshi Abe ◽

Akira Matsuda ◽

Satoshi Shuto

Keyword(s):

Lewis Acid ◽

Efficient Synthesis ◽

Faculty Opinions recommendation of Stereochemical diversity-oriented conformational restriction strategy. Development of potent histamine H3 and/or H4 receptor antagonists with an imidazolylcyclopropane structure.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.1046519.496492 ◽

2006 ◽

Author(s):

Andrew Combs

Keyword(s):

Strategy Development ◽

Receptor Antagonists ◽

Restriction Strategy ◽

H4 Receptor ◽

Histamine H3

A Conformational Restriction Strategy for the Identification of a Highly Selective Pyrimido-pyrrolo-oxazine mTOR Inhibitor

Journal of Medicinal Chemistry ◽

10.1021/acs.jmedchem.9b00972 ◽

2019 ◽

Vol 62 (18) ◽

pp. 8609-8630 ◽

Cited By ~ 5

Author(s):

Chiara Borsari ◽

Denise Rageot ◽

Alix Dall’Asen ◽

Thomas Bohnacker ◽

Anna Melone ◽

...

Keyword(s):

Mtor Inhibitor ◽

Efficient synthesis of β-C-glucosides via radical cyclization with a silicon tether based on the conformational restriction strategy

Tetrahedron Letters ◽

10.1016/j.tetlet.2005.07.087 ◽

2005 ◽

Vol 46 (38) ◽

pp. 6555-6558 ◽

Cited By ~ 7

Author(s):

Masaru Terauchi ◽

Akira Matsuda ◽

Satoshi Shuto

Keyword(s):

Radical Cyclization ◽

Efficient Synthesis ◽