Design, synthesis, and pharmacological evaluation of potent xanthone dicarboxylic acid leukotriene B4 receptor antagonists

QSAR Study of ortho-phenylphenol leukotriene B4 receptor antagonists

10.1016/s0960-894x(01)80850-7 ◽

1994 ◽

Vol 4 (6) ◽

pp. 795-800 ◽

Cited By ~ 4

Author(s):

James H. Wikel ◽

Michael J. Sofia ◽

David L. Saussy ◽

Kerry G. Bemis

Keyword(s):

Leukotriene B4 ◽

Receptor Antagonists ◽

Qsar Study ◽

Synthesis and pharmacologic activity of hydroxyacetophenone-substituted benzophenone/xanthone leukotriene B4 receptor antagonists

10.1016/s0960-894x(01)80999-9 ◽

1993 ◽

Vol 3 (10) ◽

pp. 1981-1984 ◽

Cited By ~ 2

Author(s):

J. Scott Sawyer ◽

Ronald F. Baldwin ◽

Larry L. Froelich ◽

David L. Saussy ◽

William T. Jackson

Keyword(s):

Leukotriene B4 ◽

Receptor Antagonists ◽

Pharmacologic Activity ◽

Hydroxymethyl bioisosteres of phenolic GluN2B-selective NMDA receptor antagonists: Design, synthesis and pharmacological evaluation

European Journal of Medicinal Chemistry ◽

10.1016/j.ejmech.2017.12.054 ◽

2018 ◽

Vol 144 ◽

pp. 672-681 ◽

Cited By ~ 7

Author(s):

Louisa Temme ◽

Bastian Frehland ◽

Dirk Schepmann ◽

Dina Robaa ◽

Wolfgang Sippl ◽

...

Keyword(s):

Nmda Receptor ◽

Nmda Receptor Antagonists ◽

Receptor Antagonists ◽

Design Synthesis ◽

Pharmacological Evaluation

-alkoxyphenol leukotriene B4 receptor antagonists: effect of a chroman carboxylic acid.

10.1016/s0960-894x(00)80454-0 ◽

1992 ◽

Vol 2 (12) ◽

pp. 1675-1680 ◽

Cited By ~ 8

Author(s):

Michael J. Sofia ◽

David L. Saussy ◽

William T. Jackson ◽

Philip Marder ◽

Steven A. Silbaugh ◽

...

Keyword(s):

Carboxylic Acid ◽

Leukotriene B4 ◽

Receptor Antagonists ◽

Dual Sigma-1 receptor antagonists and hydrogen sulfide-releasing compounds for pain treatment: Design, synthesis, and pharmacological evaluation

European Journal of Medicinal Chemistry ◽

10.1016/j.ejmech.2021.114091 ◽

2022 ◽

pp. 114091

Author(s):

Maria Dichiara ◽

Antonia Artacho-Cordón ◽

Rita Turnaturi ◽

Miriam Santos-Caballero ◽

Rafael González-Cano ◽

...

Keyword(s):

Hydrogen Sulfide ◽

Pain Treatment ◽

Receptor Antagonists ◽

Design Synthesis ◽

Sigma 1 Receptor ◽

Sigma 1 ◽

Treatment Design

Rational Design, Synthesis, and Pharmacological Evaluation of 2-Azanorbornane-3-exo,5-endo-dicarboxylic Acid: A Novel Conformationally Restricted Glutamic Acid Analogue

The Journal of Organic Chemistry ◽

10.1021/jo026509p ◽

2003 ◽

Vol 68 (4) ◽

pp. 1489-1495 ◽

Cited By ~ 26

Author(s):

Lennart Bunch ◽

Tommy Liljefors ◽

Jeremy R. Greenwood ◽

Karla Frydenvang ◽

Hans Bräuner-Osborne ◽

...

Keyword(s):

Glutamic Acid ◽

Dicarboxylic Acid ◽

Rational Design ◽

Design Synthesis ◽

Conformationally Restricted ◽

Acid Analogue

Commonly used leukotriene B4 receptor antagonists possess intrinsic activity as agonists in human endothelial cells: Effects on calcium transients, adhesive events and mediator release

Prostaglandins Leukotrienes and Essential Fatty Acids ◽

10.1016/j.plefa.2010.11.003 ◽

2011 ◽

Vol 84 (3-4) ◽

pp. 109-112 ◽

Cited By ~ 7

Author(s):

Anne-Sofie Johansson ◽

Jesper Z. Haeggström ◽

Jan Palmblad

Keyword(s):

Endothelial Cells ◽

Leukotriene B4 ◽

Mediator Release ◽

Calcium Transients ◽

Intrinsic Activity ◽

Human Endothelial Cells ◽

Receptor Antagonists ◽

Synthesis and pharmacological profile of new 1,3-disubstituted cyclohexanes as leukotriene B4 receptor antagonists

10.1016/0960-894x(96)00424-6 ◽

1996 ◽

Vol 6 (19) ◽

pp. 2349-2354 ◽

Cited By ~ 6

Author(s):

J.M. Poudrel ◽

P. Hullot ◽

J.P. Vidal ◽

J.P. Girard ◽

J.C. Rossi ◽

...

Keyword(s):

Leukotriene B4 ◽

Pharmacological Profile ◽

Receptor Antagonists ◽

Design, Synthesis, and Pharmacological Evaluation of Piperidin-4-yl amino aryl sulfonamides: Novel, Potent, Selective, Orally Active, and Brain Penetrant 5-HT6 Receptor Antagonists

Journal of Medicinal Chemistry ◽

10.1021/jm300955x ◽

2012 ◽

Vol 55 (21) ◽

pp. 9255-9269 ◽

Cited By ~ 12

Author(s):

Ramakrishna Nirogi ◽

Anil Shinde ◽

Anand Daulatabad ◽

Ramasastri Kambhampati ◽

Parandhama Gudla ◽

...

Keyword(s):

Receptor Antagonists ◽

Design Synthesis ◽

Orally Active

N-aryl cinnamides: A novel class of rigid and highly potent leukotriene B4 receptor antagonists

10.1016/s0960-894x(97)00134-0 ◽

1997 ◽

Vol 7 (7) ◽

pp. 949-954 ◽

Cited By ~ 6

Author(s):

Paul D. Greenspan ◽

Alan J. Main ◽

Shripad S. Bhagwat ◽

Lester I. Barsky ◽

Robert A. Doti ◽

...

Keyword(s):

Leukotriene B4 ◽

Receptor Antagonists ◽