Structure−Activity Relationships of Cyclic Peptide-Based Chemokine Receptor CXCR4 Antagonists:  Disclosing the Importance of Side-Chain and Backbone Functionalities

2007 ◽  
Vol 50 (2) ◽  
pp. 192-198 ◽  
Author(s):  
Satoshi Ueda ◽  
Shinya Oishi ◽  
Zi-xuan Wang ◽  
Takanobu Araki ◽  
Hirokazu Tamamura ◽  
...  
Keyword(s):  
Chemokine Receptor ◽  
Cyclic Peptide ◽  
Side Chain ◽  
Structure Activity Relationships ◽  
Chemokine Receptor Cxcr4 ◽  
Structure Activity ◽  
Cxcr4 Antagonists

Synthesis and Structure−Activity Relationships of Phenylenebis(methylene)- Linked Bis-azamacrocycles That Inhibit HIV-1 and HIV-2 Replication by Antagonism of the Chemokine Receptor CXCR4

1999 ◽  
Vol 42 (19) ◽  
pp. 3971-3981 ◽  
Author(s):  
Gary J. Bridger ◽  
Renato T. Skerlj ◽  
Sreenivasan Padmanabhan ◽  
Stephen A. Martellucci ◽  
Geoffrey W. Henson ◽  
...  
Keyword(s):  
Chemokine Receptor ◽  
Structure Activity Relationships ◽  
Chemokine Receptor Cxcr4 ◽  
Structure Activity ◽  
Hiv 1

Potential antitumor agents. 63. Structure-activity relationships for side-chain analogs of the colon 38 active agent 9-oxo-9H-xanthene-4-acetic acid

1991 ◽  
Vol 34 (9) ◽  
pp. 2864-2870 ◽  
Author(s):  
Gordon W. Rewcastle ◽  
Graham J. Atwell ◽  
Bruce C. Baguley ◽  
Maruta Boyd ◽  
Lindy L. Thomsen ◽  
...  
Keyword(s):  
Acetic Acid ◽  
Antitumor Agents ◽  
Active Agent ◽  
Side Chain ◽  
Structure Activity Relationships ◽  
Structure Activity ◽  
Potential Antitumor

Structure–activity relationships of the peptide deformylase inhibitor BB-3497: modification of the methylene spacer and the P1′ side chain

2003 ◽  
Vol 13 (16) ◽  
pp. 2709-2713 ◽  
Author(s):  
Stephen J. Davies ◽  
Andrew P. Ayscough ◽  
R.Paul Beckett ◽  
Ryan A. Bragg ◽  
John M. Clements ◽  
...  
Keyword(s):  
Peptide Deformylase ◽  
Side Chain ◽  
Structure Activity Relationships ◽  
Structure Activity

Ketamine esters and amides as short-acting anaesthetics: Structure-activity relationships for the side-chain

2019 ◽  
Vol 27 (7) ◽  
pp. 1226-1231 ◽  
Author(s):  
Ivaylo V. Dimitrov ◽  
Martyn G. Harvey ◽  
Logan J. Voss ◽  
James W. Sleigh ◽  
Michael J. Bickerdike ◽  
...  
Keyword(s):  
Side Chain ◽  
Short Acting ◽  
Structure Activity Relationships ◽  
Structure Activity

Structure-Activity Relationships in Side-Chain-Modified Epothilone Analogues—How Important is the Position of the Nitrogen Atom?

ChemMedChem ◽  
2006 ◽  
Vol 1 (1) ◽  
pp. 37-40 ◽  
Author(s):  
Guido Bold ◽  
Séverine Wojeik ◽  
Giorgio Caravatti ◽  
Renate Lindauer ◽  
Claire Stierlin ◽  
...  
Keyword(s):  
Nitrogen Atom ◽  
Side Chain ◽  
Structure Activity Relationships ◽  
Structure Activity

Structure–activity relationships of side-chain modified didemnins

2001 ◽  
Vol 11 (2) ◽  
pp. 231-234 ◽  
Author(s):  
Xiaobin Ding ◽  
Matthew D. Vera ◽  
Bo Liang ◽  
Yuming Zhao ◽  
Michael S. Leonard ◽  
...  
Keyword(s):  
Side Chain ◽  
Structure Activity Relationships ◽  
Structure Activity

scholarly journals Structure–Activity Relationships for Side Chain Oxysterol Agonists of the Hedgehog Signaling Pathway

2012 ◽  
Vol 3 (10) ◽  
pp. 828-833 ◽  
Author(s):  
Audrey Corman ◽  
Albert M. DeBerardinis ◽  
M. Kyle Hadden
Keyword(s):  
Signaling Pathway ◽  
Hedgehog Signaling ◽  
Side Chain ◽  
Hedgehog Signaling Pathway ◽  
Structure Activity Relationships ◽  
Structure Activity
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