Design, Synthesis, and Biological Evaluation of Erythrina Alkaloid Analogues as Neuronal Nicotinic Acetylcholine Receptor Antagonists

Biological Evaluation ◽

Receptor Antagonists ◽

Nicotinic Acetylcholine ◽

Design Synthesis ◽

Synthesis And Biological Evaluation ◽

Erythrina Alkaloid

Design, synthesis and biological evaluation of 1,4-Diazobicylco[3.2.2]nonane derivatives as α7-Nicotinic acetylcholine receptor PET/CT imaging agents and agonists for Alzheimer's disease

European Journal of Medicinal Chemistry ◽

10.1016/j.ejmech.2018.09.064 ◽

2018 ◽

Vol 159 ◽

pp. 255-266 ◽

Cited By ~ 2

Author(s):

Shuxia Wang ◽

Yu Fang ◽

Huan Wang ◽

Hang Gao ◽

Guohua Jiang ◽

...

Keyword(s):

Acetylcholine Receptor ◽

Biological Evaluation ◽

Ct Imaging ◽

Imaging Agents ◽

Α7 Nicotinic Acetylcholine Receptor ◽

Nicotinic Acetylcholine ◽

Design Synthesis ◽

Pet Ct ◽

Structural Biology-Guided Design, Synthesis, and Biological Evaluation of Novel Insect Nicotinic Acetylcholine Receptor Orthosteric Modulators

Journal of Medicinal Chemistry ◽

10.1021/acs.jmedchem.1c01767 ◽

2022 ◽

Author(s):

Mark Montgomery ◽

Stefano Rendine ◽

Christoph T. Zimmer ◽

Jan Elias ◽

Jürgen Schaetzer ◽

...

Keyword(s):

Acetylcholine Receptor ◽

Structural Biology ◽

Biological Evaluation ◽

Nicotinic Acetylcholine ◽

Design Synthesis ◽

Synthesis and Pharmacological Evaluation of DHβE Analogues as Neuronal Nicotinic Acetylcholine Receptor Antagonists

ACS Medicinal Chemistry Letters ◽

10.1021/ml500094c ◽

2014 ◽

Vol 5 (7) ◽

pp. 766-770 ◽

Cited By ~ 15

Author(s):

Tue Heesgaard Jepsen ◽

Anders A. Jensen ◽

Mads Henrik Lund ◽

Emil Glibstrup ◽

Jesper Langgaard Kristensen

Keyword(s):

Acetylcholine Receptor ◽

Receptor Antagonists ◽

Nicotinic Acetylcholine ◽

Pharmacological Evaluation

Synthesis and biological evaluation of novel hybrids of highly potent and selective α4β2-Nicotinic acetylcholine receptor (nAChR) partial agonists

European Journal of Medicinal Chemistry ◽

10.1016/j.ejmech.2016.09.016 ◽

2016 ◽

Vol 124 ◽

pp. 689-697 ◽

Cited By ~ 6

Author(s):

Han-Kun Zhang ◽

J. Brek Eaton ◽

Allison Fedolak ◽

Hendra Gunosewoyo ◽

Oluseye K. Onajole ◽

...

Keyword(s):

Acetylcholine Receptor ◽

Biological Evaluation ◽

Nicotinic Acetylcholine ◽

Partial Agonists ◽

Synthesis and biological evaluation of 9-fluorenone derivatives for SPECT imaging of α7-nicotinic acetylcholine receptor

Bioorganic & Medicinal Chemistry Letters ◽

10.1016/j.bmcl.2019.126724 ◽

2019 ◽

Vol 29 (23) ◽

pp. 126724

Author(s):

Hang Gao ◽

Shuxia Wang ◽

Yueheng Qi ◽

Guoxue He ◽

Bingchao Qiang ◽

...

Keyword(s):

Acetylcholine Receptor ◽

Biological Evaluation ◽

Spect Imaging ◽

Α7 Nicotinic Acetylcholine Receptor ◽

Nicotinic Acetylcholine ◽

Recent developments in neuronal nicotinic acetylcholine receptor antagonists

Expert Opinion on Therapeutic Patents ◽

10.1517/13543776.10.10.1561 ◽

2000 ◽

Vol 10 (10) ◽

pp. 1561-1581 ◽

Cited By ~ 34

Author(s):

Linda P Dwoskin ◽

Rui Xu ◽

Joshua T Ayers ◽

Peter A Crooks

Keyword(s):

Acetylcholine Receptor ◽

Receptor Antagonists ◽

Nicotinic Acetylcholine ◽

Recent Developments

Identification of polypeptides associated with a putative neuronal nicotinic acetylcholine receptor.

Journal of Biological Chemistry ◽

10.1016/s0021-9258(18)33771-2 ◽

1982 ◽

Vol 257 (19) ◽

pp. 11390-11394

Author(s):

H Betz ◽

D Graham ◽

H Rehm

Keyword(s):

Acetylcholine Receptor ◽

Nicotinic Acetylcholine

5371188 Neuronal nicotinic acetylcholine receptor compositions

Biotechnology Advances ◽

10.1016/0734-9750(96)84630-1 ◽

1995 ◽

Vol 13 (4) ◽

pp. 716

Keyword(s):

Acetylcholine Receptor ◽

Nicotinic Acetylcholine

Genetic association analysis of tagging SNPs in alpha4 and beta2 subunits of neuronal nicotinic acetylcholine receptor genes (CHRNA4 and CHRNB2) with schizophrenia in the Japanese population

Journal of Neural Transmission ◽

10.1007/s00702-008-0114-8 ◽

2008 ◽

Vol 115 (10) ◽

pp. 1457-1461 ◽

Cited By ~ 8

Author(s):

Taro Kishi ◽

Masashi Ikeda ◽

Tsuyoshi Kitajima ◽

Yoshio Yamanouchi ◽

Yoko Kinoshita ◽

...

Keyword(s):

Acetylcholine Receptor ◽

Genetic Association ◽

Association Analysis ◽

Japanese Population ◽

Genetic Association Analysis ◽

Nicotinic Acetylcholine

N-(2,7-Dimethyl-2-alkyl-2H-chromen-6-yl)sulfonamide derivatives as selective serotonin 5-HT6 receptor antagonists: design, synthesis, and biological evaluation

Journal of Molecular Structure ◽

10.1016/j.molstruc.2021.131417 ◽

2021 ◽

pp. 131417

Author(s):

Aizhan Abdildinova ◽

Young Chang Kim ◽

Gee-Hyung Lee ◽

Woo-Kyu Park ◽

Heeyeong Cho ◽

...

Keyword(s):

Biological Evaluation ◽

Selective Serotonin ◽

Receptor Antagonists ◽

Design Synthesis ◽