Structural Biology-Guided Design, Synthesis, and Biological Evaluation of Novel Insect Nicotinic Acetylcholine Receptor Orthosteric Modulators

Biological Evaluation ◽

Nicotinic Acetylcholine ◽

Design Synthesis ◽

Design, synthesis and biological evaluation of 1,4-Diazobicylco[3.2.2]nonane derivatives as α7-Nicotinic acetylcholine receptor PET/CT imaging agents and agonists for Alzheimer's disease

European Journal of Medicinal Chemistry ◽

10.1016/j.ejmech.2018.09.064 ◽

2018 ◽

Vol 159 ◽

pp. 255-266 ◽

Cited By ~ 2

Author(s):

Shuxia Wang ◽

Yu Fang ◽

Huan Wang ◽

Hang Gao ◽

Guohua Jiang ◽

...

Keyword(s):

Acetylcholine Receptor ◽

Biological Evaluation ◽

Ct Imaging ◽

Imaging Agents ◽

Α7 Nicotinic Acetylcholine Receptor ◽

Nicotinic Acetylcholine ◽

Design Synthesis ◽

Pet Ct ◽

Design, Synthesis, and Biological Evaluation of Erythrina Alkaloid Analogues as Neuronal Nicotinic Acetylcholine Receptor Antagonists

Journal of Medicinal Chemistry ◽

10.1021/jm4013592 ◽

2013 ◽

Vol 56 (23) ◽

pp. 9673-9682 ◽

Cited By ~ 32

Author(s):

François Crestey ◽

Anders A. Jensen ◽

Morten Borch ◽

Jesper Tobias Andreasen ◽

Jacob Andersen ◽

...

Keyword(s):

Acetylcholine Receptor ◽

Biological Evaluation ◽

Neuronal Nicotinic Acetylcholine Receptor ◽

Receptor Antagonists ◽

Nicotinic Acetylcholine ◽

Design Synthesis ◽

Synthesis And Biological Evaluation ◽

Erythrina Alkaloid

Synthesis and biological evaluation of novel hybrids of highly potent and selective α4β2-Nicotinic acetylcholine receptor (nAChR) partial agonists

European Journal of Medicinal Chemistry ◽

10.1016/j.ejmech.2016.09.016 ◽

2016 ◽

Vol 124 ◽

pp. 689-697 ◽

Cited By ~ 6

Author(s):

Han-Kun Zhang ◽

J. Brek Eaton ◽

Allison Fedolak ◽

Hendra Gunosewoyo ◽

Oluseye K. Onajole ◽

...

Keyword(s):

Acetylcholine Receptor ◽

Biological Evaluation ◽

Nicotinic Acetylcholine ◽

Partial Agonists ◽

Synthesis and biological evaluation of 9-fluorenone derivatives for SPECT imaging of α7-nicotinic acetylcholine receptor

Bioorganic & Medicinal Chemistry Letters ◽

10.1016/j.bmcl.2019.126724 ◽

2019 ◽

Vol 29 (23) ◽

pp. 126724

Author(s):

Hang Gao ◽

Shuxia Wang ◽

Yueheng Qi ◽

Guoxue He ◽

Bingchao Qiang ◽

...

Keyword(s):

Acetylcholine Receptor ◽

Biological Evaluation ◽

Spect Imaging ◽

Α7 Nicotinic Acetylcholine Receptor ◽

Nicotinic Acetylcholine ◽

Design, synthesis, structure–activity relationship, and in vivo activity of azabicyclic aryl amides as α7 nicotinic acetylcholine receptor agonists

Bioorganic & Medicinal Chemistry ◽

10.1016/j.bmc.2006.09.019 ◽

2006 ◽

Vol 14 (24) ◽

pp. 8219-8248 ◽

Cited By ~ 63

Author(s):

Daniel P. Walker ◽

Donn G. Wishka ◽

David W. Piotrowski ◽

Shaojuan Jia ◽

Steven C. Reitz ◽

...

Keyword(s):

Acetylcholine Receptor ◽

Structure Activity Relationship ◽

Activity Relationship ◽

Α7 Nicotinic Acetylcholine Receptor ◽

Nicotinic Acetylcholine ◽

Design Synthesis ◽

Receptor Agonists ◽

Structure Activity

SAR and biological evaluation of SEN12333/WAY-317538: Novel alpha 7 nicotinic acetylcholine receptor agonist

Bioorganic & Medicinal Chemistry ◽

10.1016/j.bmc.2009.05.040 ◽

2009 ◽

Vol 17 (14) ◽

pp. 5247-5258 ◽

Cited By ~ 26

Author(s):

Simon N. Haydar ◽

Chiara Ghiron ◽

Laura Bettinetti ◽

Hendrick Bothmann ◽

Thomas A. Comery ◽

...

Keyword(s):

Acetylcholine Receptor ◽

Receptor Agonist ◽

Biological Evaluation ◽

Nicotinic Acetylcholine ◽

Alpha 7

Design, Synthesis and Discovery of Picomolar Selective α4β2 Nicotinic Acetylcholine Receptor Ligands

Journal of Medicinal Chemistry ◽

10.1021/jm4008455 ◽

2013 ◽

Vol 56 (21) ◽

pp. 8404-8421 ◽

Cited By ~ 12

Author(s):

Venkata M. Yenugonda ◽

Yingxian Xiao ◽

Edward D. Levin ◽

Amir H. Rezvani ◽

Thao Tran ◽

...

Keyword(s):

Acetylcholine Receptor ◽

Receptor Ligands ◽

Nicotinic Acetylcholine ◽

Design Synthesis

Design, synthesis, and electrophysiological evaluation of NS6740 derivatives: Exploration of the structure-activity relationship for alpha7 nicotinic acetylcholine receptor silent activation

European Journal of Medicinal Chemistry ◽

10.1016/j.ejmech.2020.112669 ◽

2020 ◽

Vol 205 ◽

pp. 112669

Author(s):

Maria Chiara Pismataro ◽

Nicole A. Horenstein ◽

Clare Stokes ◽

Marta Quadri ◽

Marco De Amici ◽

...

Keyword(s):

Acetylcholine Receptor ◽

Structure Activity Relationship ◽

Activity Relationship ◽

Nicotinic Acetylcholine ◽

Design Synthesis ◽

Alpha7 Nicotinic Acetylcholine Receptor ◽

Structure Activity

Corrigendum to “SAR and biological evaluation of SEN12333/WAY-317538: Novel alpha 7 nicotinic acetylcholine receptor agonist” [Bioorg. Med. Chem. 17 (2009) 5247]

Bioorganic & Medicinal Chemistry ◽

10.1016/j.bmc.2009.11.042 ◽

2010 ◽

Vol 18 (2) ◽

pp. 985

Author(s):

Simon N. Haydar ◽

Chiara Ghiron ◽

Laura Bettinetti ◽

Hendrick Bothmann ◽

Thomas A. Comery ◽

...

Keyword(s):

Acetylcholine Receptor ◽

Receptor Agonist ◽

Biological Evaluation ◽

Nicotinic Acetylcholine ◽

Alpha 7

Efficacy of Varenicline, an α4β2 Nicotinic Acetylcholine Receptor Partial Agonist, vs Placebo or Sustained-Release Bupropion for Smoking Cessation: A Randomized Controlled Trial

Yearbook of Pulmonary Disease ◽

10.1016/s8756-3452(08)70598-x ◽

2008 ◽

Vol 2008 ◽

pp. 109-110

Author(s):

L.T. Tanoue

Keyword(s):

Randomized Controlled Trial ◽

Smoking Cessation ◽

Sustained Release ◽

Acetylcholine Receptor ◽

Partial Agonist ◽

Controlled Trial ◽

Nicotinic Acetylcholine ◽

Randomized Controlled