1-Sulfonyl-4-acylpiperazines as Selective Cannabinoid-1 Receptor (CB1R) Inverse Agonists for the Treatment of Obesity

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Joan M. Fletcher ◽  
Tung M. Fong ◽  
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Cannabinoid 1 Receptor ◽  
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Jochem Alsenz ◽  
Mirjana Andjelkovic ◽  
Stefanie Bendels ◽  
Agnès Bénardeau ◽  
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Inverse Agonists ◽  
Cannabinoid 1 Receptor ◽  
Treatment Of Obesity

Optimization of imidazole amide derivatives as cannabinoid-1 receptor antagonists for the treatment of obesity

2007 ◽  
Vol 17 (10) ◽  
pp. 2706-2711 ◽  
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Roger A. Smith ◽  
Zahra Fathi ◽  
Furahi Achebe ◽  
Christiana Akuche ◽  
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Cannabinoid 1 Receptor ◽  
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Identification of pyrazolo-pyrimidinones as GHS-R1a antagonists and inverse agonists for the treatment of obesity

MedChemComm ◽  
2013 ◽  
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Author(s):  
William McCoull ◽  
Peter Barton ◽  
Anders Broo ◽  
Alastair J. H. Brown ◽  
David S. Clarke ◽  
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Keyword(s):  
Inverse Agonists ◽  
Treatment Of Obesity
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