Exploring structural requirements for peripherally acting 1,5-diaryl pyrazole-containing cannabinoid 1 receptor antagonists for the treatment of obesity

2015 ◽  
Vol 19 (4) ◽  
pp. 871-893 ◽  
Author(s):  
Mayank Kumar Sharma ◽  
Prashant R. Murumkar ◽  
Rajani Giridhar ◽  
Mange Ram Yadav
Keyword(s):  
Receptor Antagonists ◽  
Structural Requirements ◽  
Cannabinoid 1 Receptor ◽  
Treatment Of Obesity

Optimization of imidazole amide derivatives as cannabinoid-1 receptor antagonists for the treatment of obesity

2007 ◽  
Vol 17 (10) ◽  
pp. 2706-2711 ◽  
Author(s):  
Roger A. Smith ◽  
Zahra Fathi ◽  
Furahi Achebe ◽  
Christiana Akuche ◽  
Su-Ellen Brown ◽  
...  
Keyword(s):  
Receptor Antagonists ◽  
Cannabinoid 1 Receptor ◽  
Amide Derivatives ◽  
Treatment Of Obesity

Biarylpyrazolyl Oxadiazole as Potent, Selective, Orally Bioavailable Cannabinoid-1 Receptor Antagonists for the Treatment of Obesity

2008 ◽  
Vol 51 (22) ◽  
pp. 7216-7233 ◽  
Author(s):  
Suk Ho Lee ◽  
Hee Jeong Seo ◽  
Sung-Han Lee ◽  
Myung Eun Jung ◽  
Ji-Hyun Park ◽  
...  
Keyword(s):  
Receptor Antagonists ◽  
Cannabinoid 1 Receptor ◽  
Orally Bioavailable ◽  
Treatment Of Obesity

Methylsulfonylpyrazolyl oxadiazoles and thiadiazoles as potent, orally bioavailable cannabinoid-1 receptor antagonists for the treatment of obesity

2009 ◽  
Vol 1 (5) ◽  
pp. 947-967 ◽  
Author(s):  
Hee Jeong Seo ◽  
Min Ju Kim ◽  
Kwang-Seop Song ◽  
Sung-Han Lee ◽  
Myung Eun Jung ◽  
...  
Keyword(s):  
Receptor Antagonists ◽  
Cannabinoid 1 Receptor ◽  
Orally Bioavailable ◽  
Treatment Of Obesity

1-Sulfonyl-4-acylpiperazines as Selective Cannabinoid-1 Receptor (CB1R) Inverse Agonists for the Treatment of Obesity

2009 ◽  
Vol 52 (8) ◽  
pp. 2550-2558 ◽  
Author(s):  
Petr Vachal ◽  
Joan M. Fletcher ◽  
Tung M. Fong ◽  
Cathy C. R.-R. Huang ◽  
Julie Lao ◽  
...  
Keyword(s):  
Inverse Agonists ◽  
Cannabinoid 1 Receptor ◽  
Treatment Of Obesity

Discovery of cannabinoid-1 receptor antagonists by virtual screening

2010 ◽  
Vol 20 (17) ◽  
pp. 5130-5132 ◽  
Author(s):  
Gil Nam Lee ◽  
Kwang Rok Kim ◽  
Sung-Hoon Ahn ◽  
Myung Ae Bae ◽  
Nam Sook Kang
Keyword(s):  
Virtual Screening ◽  
Receptor Antagonists ◽  
Cannabinoid 1 Receptor

ChemInform Abstract: Prospective Therapeutic Agents for Obesity: Molecular Modification Approaches of Centrally and Peripherally Acting Selective Cannabinoid 1 Receptor Antagonists

ChemInform ◽  
2014 ◽  
Vol 45 (29) ◽  
pp. no-no
Author(s):  
Mayank Kumar Sharma ◽  
Prashant R. Murumkar ◽  
Ashish M. Kanhed ◽  
Rajani Giridhar ◽  
Mange Ram Yadav
Keyword(s):  
Therapeutic Agents ◽  
Receptor Antagonists ◽  
Molecular Modification ◽  
Cannabinoid 1 Receptor

Synthesis and Evaluation of New Arylsulfonamidomethylcyclohexyl Derivatives as Human Neuropeptide Y Y5 Receptor Antagonists for the Treatment of Obesity.

ChemInform ◽  
2004 ◽  
Vol 35 (30) ◽  
Author(s):  
Antonio Moreno ◽  
Silvia Perez ◽  
Silvia Galiano ◽  
Laura Juanenea ◽  
Oihana Erviti ◽  
...  
Keyword(s):  
Neuropeptide Y ◽  
Receptor Antagonists ◽  
Treatment Of Obesity

Prediction and Experimental Confirmation of Novel Peripheral Cannabinoid-1 Receptor Antagonists

2019 ◽  
Vol 59 (9) ◽  
pp. 3996-4006
Author(s):  
Shayma El-Atawneh ◽  
Shira Hirsch ◽  
Rivka Hadar ◽  
Joseph Tam ◽  
Amiram Goldblum
Keyword(s):  
Experimental Confirmation ◽  
Receptor Antagonists ◽  
Cannabinoid 1 Receptor
Sign in / Sign up

Export Citation Format

Share Document