Trichloromethyltrimethylsilane, Sodium Formate, and Dimethylformamide:  A Mild, Efficient, and General Method for the Preparation of Trimethylsilyl-Protected 2,2,2-Trichloromethylcarbinols from Aldehydes and Ketones

2007 ◽  
Vol 72 (10) ◽  
pp. 3925-3928 ◽  
Author(s):  
Jérémy Kister ◽  
Charles Mioskowski
Synthesis ◽  
2020 ◽  
Vol 52 (14) ◽  
pp. 2121-2126
Author(s):  
Zhanggao Le ◽  
Zongbo Xie ◽  
Jin Lan ◽  
Guofang Jiang ◽  
Jiangnan Yang ◽  
...  

This is the first report of a simple and general method for acetalization­ of aldehydes via an α-chymotrypsin-induced reaction under mild conditions. A broad range of aromatic and heteroaromatic aldehydes have been acetalized under neutral conditions in good yields using a catalytic amount of chymotrypsin.


1981 ◽  
Vol 46 (16) ◽  
pp. 3367-3369 ◽  
Author(s):  
James H. Babler ◽  
Steven J. Sarussi

1964 ◽  
Vol 9 (1) ◽  
pp. 108-109 ◽  
Author(s):  
A. J. Sisti ◽  
John. Sawinski ◽  
Robert. Stout

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