Effects of the RGTFEGKF Inhibitor on the Structures of the Transmembrane Fragment 70−86 of Glycophorin A: An All-Atom Molecular Dynamics Study

2010 ◽  
Vol 114 (2) ◽  
pp. 1004-1009 ◽  
Author(s):  
Huiyu Li ◽  
Yin Luo ◽  
Philippe Derreumaux ◽  
Guanghong Wei
Keyword(s):  
Molecular Dynamics ◽  
Glycophorin A ◽  
Transmembrane Fragment

Modulation of glycophorin A transmembrane helix interactions by lipid bilayers: molecular dynamics calculations

2000 ◽  
Vol 302 (3) ◽  
pp. 727-746 ◽  
Author(s):  
Horia I Petrache ◽  
Alan Grossfield ◽  
Kevin R MacKenzie ◽  
Donald M Engelman ◽  
Thomas B Woolf
Keyword(s):  
Molecular Dynamics ◽  
Lipid Bilayers ◽  
Transmembrane Helix ◽  
Glycophorin A ◽  
Molecular Dynamics Calculations ◽  
Helix Interactions

scholarly journals Influence of the C-terminus of the glycophorin A transmembrane fragment on the dimerization process

2000 ◽  
Vol 9 (6) ◽  
pp. 1246-1253 ◽  
Author(s):  
Mar Orzáez ◽  
Enrique Pérez-Payá ◽  
Ismael Mingarro
Keyword(s):  
Glycophorin A ◽  
C Terminus ◽  
Transmembrane Fragment ◽  
Dimerization Process

scholarly journals In silico molecular dynamics of human glycophorin A (GPA) extracellular structure

2021 ◽  
Vol 6 ◽  
pp. 11-11
Author(s):  
Serena Ekman ◽  
Robert Flower ◽  
Stephen Mahler ◽  
Alison Gould ◽  
Ross T. Barnard ◽  
...  
Keyword(s):  
Molecular Dynamics ◽  
In Silico ◽  
Glycophorin A ◽  
Human Glycophorin

Effect of Integral Proteins on Frozen Membrane Fracture

1980 ◽  
Vol 38 ◽  
pp. 756-759 ◽  
Author(s):  
S. Kirchanski ◽  
D. Branton
Keyword(s):  
Lipid Bilayers ◽  
Freeze Fracture ◽  
Covalent Bond ◽  
Erythrocyte Membranes ◽  
Glycophorin A ◽  
Experimental Protocol ◽  
Transmembrane Glycoprotein ◽  
Bond Breakage ◽  
Human Erythrocyte Membranes ◽  
Integral Proteins

We have investigated the effect of integral membrane proteins upon the fracturing of frozen lipid bilayers. This investigation has been part of an effort to develop freeze fracture labeling techniques and to assess the possible breakage of covalent protein bonds during the freeze fracture process. We have developed an experimental protocol utilizing lectin affinity columns which should detect small amounts of covalent bond breakage during the fracture of liposomes containing purified (1) glycophorin (a transmembrane glycoprotein of human erythrocyte membranes). To fracture liposomes in bulk, frozen liposomes are ground repeatedly under liquid nitrogen. Failure to detect any significant covalent bond breakage (contrary to (2)) led us to question the effectiveness of our grinding procedure in fracturing and splitting lipid bilayers.

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